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Merck

PHR1259

チアベンダゾール

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

2-(4-チアゾリル)ベンゾイミダゾール

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この商品について

実験式(ヒル表記法):
C10H7N3S
CAS番号:
分子量:
201.25
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
205-725-8
Beilstein/REAXYS Number:
611403
MDL number:
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InChI

1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)

InChI key

WJCNZQLZVWNLKY-UHFFFAOYSA-N

SMILES string

c1ccc2[nH]c(nc2c1)-c3cscn3

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. T1410000, traceable to USP 1655000

API family

thiabendazole

CofA

current certificate can be downloaded

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

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Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Thiabendazole may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and preparations by spectrophotometric, spectrofluorimetric and chromatography techniques.

General description

Thiabendazole is an orally effective broad spectrum anthelmintic and antimycotic drug with limited side-effects.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA9062 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Environment

signalword

Warning

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

保管分類

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

名称等を表示すべき危険物及び有害物

ishl_indicated

名称等を通知すべき危険物及び有害物

ishl_notified

PHR1259-500MG-PW: + PHR1259-500MG:

jan


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Determination of 81 pharmaceutical drugs by high performance liquid chromatography coupled to mass spectrometry with hybrid triple quadrupole--linear ion trap in different types of water in Serbia
Petrovic M, et al.
The Science of the Total Environment, 468(2), 415-428 (2014)
Studies on the toxicologic and pharmacologic properties of thiabendazole
Robinson HJ, et al.
Toxicology and Applied Pharmacology, 7(1), 53-63 (1965)
Development of a spectrofluorimetric method for determination of thiabendazole in tablets
Kucukkolbasi S and Kilic E
Journal of Applied Pharmaceutical Science, 3(2), 19-19 (2013)
Mechanism of action of the fungicide thiabendazole, 2-(4?-thiazolyl) benzimidazole
Allen PM and Gottlieb D
Applied and Environmental Microbiology, 20(6), 919-926 (1970)
Suely R C Andrade et al.
Journal of pharmaceutical and biomedical analysis, 33(4), 655-665 (2003-11-19)
Three multivariate calibration methods, Principal Component Regression (PCR), the K-matrix method and Q-mode factor analysis followed by varimax and Imbrie's oblique rotations were applied to the simultaneous spectrophotometric determinations of mebendazole (MBZ)-cambendazole (CBZ) and thiabendazole (TBZ)-mebendazole in commercial samples of

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