PHR1320
アセトニトリル
Pharmaceutical Secondary Standard; Certified Reference Material
別名:
ACN, エチルニトリル, シアノメタン, シアン化メチル
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この商品について
化学式:
CH3CN
CAS番号:
分子量:
41.05
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-664-3
Beilstein/REAXYS Number:
741857
MDL number:
製品名
アセトニトリル, Pharmaceutical Secondary Standard; Certified Reference Material
InChI key
WEVYAHXRMPXWCK-UHFFFAOYSA-N
InChI
1S/C2H3N/c1-2-3/h1H3
SMILES string
CC#N
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to USP 1601340
vapor density
1.41 (vs air)
vapor pressure
72.8 mmHg ( 20 °C)
CofA
current certificate can be downloaded
autoignition temp.
973 °F
expl. lim.
16 %
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
refractive index
n20/D 1.344 (lit.)
bp
81-82 °C (lit.)
mp
−45 °C (lit.)
density
0.786 g/mL at 25 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
single component solution
storage temp.
2-30°C
Quality Level
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Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
General description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Residual Solvent - Acetonitrile is a CRM and Secondary Pharmaceutical Reference Standard, traceable and qualified against the corresponding Pharmacopeial standards. Sigma-Aldrich offers Certified Reference Materials (CRMs) for the analysis of Residual Solvents. A comprehensive Certificate of Analysis offers details of the methodology and results of the qualification.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA0679 in the slot below. This is an example certificate only and may not be the lot that you receive.
保管分類
10 - Combustible liquids
wgk
WGK 1
flash_point_f
188.6 °F - closed cup
flash_point_c
87 °C - closed cup
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Elke H J Krekels et al.
Clinical pharmacokinetics, 53(6), 553-563 (2014-02-06)
From a previously validated paediatric population pharmacokinetic model, it was derived that non-linear morphine maintenance doses of 5 μg/kg(1.5)/h, with a 50 % dose reduction in neonates with a postnatal age (PNA) <10 days, yield similar morphine and metabolite concentrations
N Sorvillo et al.
Journal of thrombosis and haemostasis : JTH, 12(5), 670-679 (2014-07-01)
Acquired deficiency of ADAMTS13 causes a rare and life-threatening disorder called thrombotic thrombocytopenic purpura (TTP). Several studies have shown that aberrant glycosylation can play an important role in the pathogenesis of autoimmune diseases.N-linked glycosylation and putative O-fucosylation sites have been
Divya Subramonian et al.
Journal of proteome research, 13(9), 3905-3918 (2014-07-30)
SUMOylation is an essential posttranslational modification and regulates many cellular processes. Dysregulation of SUMOylation plays a critical role in metastasis, yet how its perturbation affects this lethal process of cancer is not well understood. We found that SUMO-2/3 modification is
Changting Xiao et al.
Diabetes, 63(7), 2394-2401 (2014-03-04)
The dipeptidyl peptidase-4 inhibitor sitagliptin, an antidiabetic agent, which lowers blood glucose levels, also reduces postprandial lipid excursion after a mixed meal. The underlying mechanism of this effect, however, is not clear. This study examined the production and clearance of
Hélène Hall et al.
Brain : a journal of neurology, 137(Pt 9), 2493-2508 (2014-07-27)
The neuropathological substrate of dementia in patients with Parkinson's disease is still under debate, particularly in patients with insufficient alternate neuropathology for other degenerative dementias. In patients with pure Lewy body Parkinson's disease, previous post-mortem studies have shown that dopaminergic
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