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Merck

PHR1435

3-(α-アセトニルベンジル)-4-ヒドロキシクマリン ナトリウム塩

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

4-ヒドロキシ-3-(3-オキソ-1-フェニルブチル)クマリン

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この商品について

化学式:
C19H15O4Na
CAS番号:
分子量:
330.31
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
204-929-4
MDL number:
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Quality Level

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. W0100000, traceable to USP 1719000

API family

warfarin

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Na].CC(=O)CC(c1ccccc1)C2=C(O)c3ccccc3OC2=O

InChI

1S/C19H16O4.Na/c1-12(20)11-15(13-7-3-2-4-8-13)17-18(21)14-9-5-6-10-16(14)23-19(17)22;/h2-10,15,21H,11H2,1H3;/q;+1/p-1

InChI key

KYITYFHKDODNCQ-UHFFFAOYSA-M

Gene Information

human ... VKORC1(79001)

General description

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards. Warfarin Sodium is an anticoagulant rodenticide, commonly used for the control of rodents such as rats, mice, etc. in surroundings, commercial and industrial sites.

Application

Warfarin Sodium may be used pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using square-wave adsorptive cathodic stripping voltammetry.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA2743 in the slot below. This is an example certificate only and may not be the lot that you receive.


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wgk

WGK 3

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Aquatic Chronic 3 - Repr. 1B

保管分類

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable



試験成績書(COA)

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Urszula Śliwińska-Hill et al.
Journal of biomolecular structure & dynamics, 37(14), 3731-3739 (2018-09-22)
The interaction between glycated human serum albumin (gHSA) and folic acid (FA) was investigated by various spectroscopic techniques, such as fluorescence, circular dichroism, UV-vis absorption spectroscopy and electrophoretic light scattering technique. These methods characterize the binding properties of an albumin-folic
Assay of anti-coagulant drug warfarin sodium in pharmaceutical formulation and human biological fluids by square-wave adsorptive cathodic stripping voltammetry
Ghoneim MM and Tawfik A
Analytica Chimica Acta, 511(1), 63-69 (2004)
Sittig's Handbook of Pesticides and Agricultural Chemicals (2014)