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Merck

PHR1462

クレアチニン

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

クレアチニン, 2-アミノ-1-メチル-2-イミダゾリン-4-オン, 2-イミノ-1-メチルイミダゾリジン-4-オン, 2-イミノ-N-メチルヒダントイン

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この商品について

実験式(ヒル表記法):
C4H7N3O
CAS番号:
分子量:
113.12
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-466-7
Beilstein/REAXYS Number:
112061
MDL number:
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Quality Level

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1150353

API family

creatinine

CofA

current certificate can be downloaded

packaging

pkg of 1 g

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

295 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CN1CC(=O)N=C1N

InChI

1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)

InChI key

DDRJAANPRJIHGJ-UHFFFAOYSA-N

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Creatinine is a by-product produced during the metabolism of creatine phosphate in muscle. It is excreted through urine, and serum creatinine level is most common indicator of renal health.

Application

Creatinine may be used as a pharmaceutical reference standard for the determination of the analyte in biological fluids by spectrophotometry, and high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA3010 in the slot below. This is an example certificate only and may not be the lot that you receive.


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保管分類

11 - Combustible Solids

wgk

WGK 3

flash_point_f

554.0 °F - closed cup

flash_point_c

290 °C - closed cup



試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

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Improved HPLC method for the simultaneous determination of allantoin, uric acid and creatinine in cattle urine
George SK
Journal of Chromatography. B, Biomedical Sciences and Applications, 832(1), 134-137 (2006)
A simplified method for HPLC determination of creatinine in mouse serum
Yuen PST, et al.
American Journal of Physiology: Renal Physiology, 286(6), F1116-F1119 (2004)
Creatinine
Clinical Veterinary Advisor, 615-615 (2013)