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PHR1533

コレステロール

Name: コレステロール
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

コレステロール, 3β-ヒドロキシ-5-コレステン, 5-コレステン-3β-オール

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この商品について

実験式（ヒル表記法）:

C₂₇H₄₆O

CAS番号:

57-88-5

分子量:

386.65

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329823445

EC Number:

200-353-2

Beilstein/REAXYS Number:

1915888

MDL number:

MFCD00003646

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特性

Quality Segment

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. C2155000, traceable to USP 1131960

API family

cholesterol

form

powder

CofA

current certificate can be downloaded

packaging

pkg of 500 mg

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

bp

360 °C (lit.)

mp

147-149 °C (lit.)

solubility

water: soluble 0.00003 g/L at 20 °C

density

1.067 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

-10 to -25°C

SMILES string

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1

InChI key

HVYWMOMLDIMFJA-DPAQBDIFSA-N

詳細

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Cholesterol is a waxy material that belongs to the class of sterol-lipids found naturally in foods from animal sources, such as egg yolks, meat, and cheese. It serves as a precursor for the biosynthesis of steroid hormones, bile acid and vitamin D.

Application

Cholesterol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and food products by gas chromatography, or by high performance liquid chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

すべての生体膜の主成分。脳脂質全体の約25%はコレステロ-ルです。

Analysis Note

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC0249 in the slot below. This is an example certificate only and may not be the lot that you receive.

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保管分類

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c