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Merck

PHR1695

Phenylephrine Related Compound C

Pharmaceutical Secondary Standard; Certified Reference Material

別名:

1-(3-Hydroxyphenyl)-2-(methylamino)ethanone hydrochloride, Phenylephrone hydrochloride, 3′-Hydroxyphenyl-2-methylaminoacetophenone hydrochloride

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この商品について

実験式（ヒル表記法）:
C9H11NO2 · HCl
CAS番号:
94240-17-2
分子量:
201.65
UNSPSC Code:
41116107
NACRES:
NA.24

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製品名

Phenylephrine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

SMILES string

[Cl-].N(CC(=O)c1cc(ccc1)O)C.[H+]

InChI

1S/C9H11NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,10-11H,6H2,1H3;1H

InChI key

DEOGEZWYKPQJLP-UHFFFAOYSA-N

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to USP 1533024

API family

phenylephrine

CofA

current certificate can be downloaded

packaging

pkg of 50 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

Quality Level

300

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Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Application

This pharmaceutical secondary standard can also be used as follows:

  • Impurity profiling of diphenhydramine and phenylephrine hydrochloride oral solutions using ultra-high performance liquid chromatography (UHPLC)

General description

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

It is an impurity of the widely used decongestant drug― phenylephrine, a selective α1-adrenergic receptor agonist.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
To see an example of a Certificate of Analysis for this material enter LRAC2623 in the slot below. This is an example certificate only and may not be the lot that you receive.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H317

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1

保管分類

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

試験成績書（COA）

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Yang Xiao et al.
Journal of cellular biochemistry, 118(11), 3899-3910 (2017-04-09)
Lack of effective anti-cardiac hypertrophy drugs creates a major cause for the increasing prevalence of heart failure. In the present study, we determined the anti-hypertrophy and anti-fibrosis potential of a natural plant triterpenoid, Cucurbitacin B both in vitro and in
Qing-Qing Wu et al.
British journal of pharmacology, 175(9), 1548-1566 (2018-02-16)
Aucubin, the predominant component of Eucommia ulmoides Oliv., has been shown to have profound effects on oxidative stress. As oxidative stress has previously been demonstrated to contribute to acute and chronic myocardial injury, we tested the effects of aucubin on

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