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Merck

STS0204

TWEEN® 80

greener alternative

viscous liquid

別名:

POE (20) ソルビタンモノオレエート, ポリエチレングリコールソルビタンモノオレアート, ポリオキシエチレンソルビタンモノオレアート, ポリソルベート80

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この商品について

CAS番号:
9005-65-6
UNSPSC Code:
12161902
NACRES:
NA.28
MDL number:
MFCD00082107

主要文書

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製品名

TWEEN® 80, viscous liquid

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

SMILES string

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI key

RGPBUVUVZKQNHD-MDZDMXLPSA-N

description

non-ionic

assay

≥58%

form

viscous liquid

mol wt

micellar avg mol wt 79.000
average mol wt 1310

composition

Oleic acid, ≥58.0% (balance primarily linoleic, palmitic, and stearic acids)

greener alternative product characteristics

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

CMC

0.012 mM (20-25°C)

viscosity

300—500 cP(25 °C)

transition temp

cloud point 65 °C

solubility

water: 100 mg/mL, clear to slightly hazy, faintly yellow

density

1.064 g/cm3

HLB

15.0

greener alternative category

Aligned,

Quality Level

200

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関連するカテゴリー

Application

Non-ionic detergent used for selective protein extraction and isolation of nuclei from mammalian cell lines.
TWEEN® 80 has been used in drug vehicle solution for specific injections in mice and rats. It has been used for the determination of esterase activity in bacterial cells.

Biochem/physiol Actions

TWEEN® 80 is a polysorbate surfactant which helps in stabilizing proteins and in protein membrane studies. It is regularly used for the extraction of membrane proteins and isolation of nuclei from cells.

Features and Benefits

  • 100 % Renewable
  • 100 % Bio-based
  • Certified to the USDA BioPreferred Program
  • Lower carbon footprint than petrochemical-based versions
  • High-purity chemical suitable for a wide variety of research applications

General description

ECO Tween® 80, also known as Polyoxyethylenesorbitan monooleate, is a bio-based, nonionic detergent manufactured from a natural fatty acid. This surfactant, derived from natural sources, provides various functional advantages, such as detergency, emulsification, and wetting. Its versatility makes it well-suited for a variety of applications in biochemical and biological research, with common uses including cell lysis, protein extraction, nuclei isolation and cell fractionation.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is a biobased surfactant and is aligned with the 7th principle of Green Chemistry "Use of Renewable Feedstocks" and the 10th principle "Design for Degradation".

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Legal Information

ECO TWEEN is a registered trademark of Croda Inc.
TWEEN is a registered trademark of Croda International PLC

保管分類

10 - Combustible liquids

wgk

WGK 1

flash_point_f

>235.4 °F - closed cup

flash_point_c

> 113 °C - closed cup

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試験成績書（COA）

Lot/Batch Number
MKCP3464

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F Rizzo et al.
Translational psychiatry, 7(8), e1189-e1189 (2017-08-02)
Attention deficit hyperactivity disorder (ADHD), Tourette syndrome (TS) as well as obsessive compulsive disorder (OCD) are co-occurring neurodevelopmental diseases that share alterations of frontocortical neurometabolites. In this longitudinal study we investigated the behavioral and neurochemical effects of aripiprazole and riluzole
Zandra Gerdes et al.
PloS one, 14(2), e0205378-e0205378 (2019-02-20)
The role of microplastic (MP) as a carrier of persistent organic pollutants (POPs) to aquatic organisms has been a topic of debate. However, the reverse POP transport can occur if relative contaminant concentrations are higher in the organism than in
HU-210 shows higher efficacy and potency than morphine after intrathecal administration in the mouse formalin test.
Guhring H et al.
European Journal of Pharmacology, 429, 127-127 (2001)
V Ryu et al.
Neuroscience, 167(4), 1227-1238 (2010-03-04)
Previous reports show that vagal afferent innervation of the stomach eventually regenerates from surviving nodose ganglion (NG) neurons after subdiaphragmatic vagotomy. Systemic capsaicin treatment destroys gastric vagal afferent neurons expressing vanilloid receptor 1 (VR1). However, it is not known whether
Christina Koester-Hegmann et al.
Frontiers in cellular neuroscience, 12, 532-532 (2019-01-29)
Exposure to hypobaric hypoxia at high altitude (above 2500 m asl) causes cognitive impairment, mostly attributed to changes in brain perfusion and consequently neuronal death. Enriched environment and voluntary exercise has been shown to improve cognitive function, to enhance brain
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