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Merck

320269

ジクロロメタン

ACS reagent, ≥99.5%, contains 40-150 ppm amylene as stabilizer

別名:

塩化メチレン

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この商品について

実験式(ヒル表記法):
CH2Cl2
CAS番号:
分子量:
84.93
UNSPSC Code:
12352101
NACRES:
NA.04
PubChem Substance ID:
EC Number:
200-838-9
Beilstein/REAXYS Number:
1730800
MDL number:
Assay:
≥99.5%
Grade:
ACS reagent
Bp:
39.8-40 °C (lit.)
Vapor pressure:
24.45 psi ( 55 °C), 6.83 psi ( 20 °C)
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InChI key

YMWUJEATGCHHMB-UHFFFAOYSA-N

InChI

1S/CH2Cl2/c2-1-3/h1H2

SMILES string

ClCCl

grade

ACS reagent

agency

suitable for EPA 1613

vapor density

2.9 (vs air)

vapor pressure

24.45 psi ( 55 °C), 6.83 psi ( 20 °C)

assay

≥99.5%

form

liquid

autoignition temp.

1223 °F

contains

40-150 ppm amylene as stabilizer

expl. lim.

22 %

dilution

(for analytical testing)

impurities

Free halogens, passes test, ≤0.0003 meq/g Titr. acid, ≤0.02% water

evapn. residue

≤0.002%

color

APHA: ≤10, clear

refractive index

n20/D 1.424 (lit.)

bp

39.8-40 °C (lit.)

mp

−95 °C (lit.)

density

1.325 g/mL at 25 °C (lit.)

Quality Level

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Application


  • Rapid and Comprehensive Analysis of 41 Harmful Substances in Multi-Matrix Products by Gas Chromatography-Mass Spectrometry Using Matrix-Matching Calibration Strategy.: This research uses gas chromatography-mass spectrometry (GC-MS) to analyze harmful substances across various matrices. Dichloromethane is employed as a solvent in the preparation phase, highlighting its application in ensuring accurate and efficient analytical results (Wang Y et al., 2024).

  • Brunonianines D-F, three new C19-diterpenoid alkaloids from the Delphinium brunonianum, with therapeutic effect on ovarian cancer in vitro and in vivo.: This study identifies new alkaloids with potential anti-cancer properties, where dichloromethane is utilized in the extraction and isolation processes. Its effectiveness in separating and preserving delicate compounds is critical for their pharmacological evaluation (Li Q et al., 2024).

  • LC-HRMS and GC-MS Profiling of Urine Free Cortisol, Cortisone, 6Β-, and 18-Hydroxycortisol for the Evaluation of Glucocorticoid and Mineralocorticoid Disorders.: Utilizes LC-HRMS and GC-MS to profile hormones in urine, with dichloromethane being crucial in the extraction process. This method ensures precision and sensitivity in hormone measurement, essential for diagnosing endocrine disorders (Casals G et al., 2024).

  • Determination of vancomycin and meropenem in serum and synovial fluid of patients with prosthetic joint infections using UPLC-MS/MS.: Features a method to measure antibiotics in biological fluids, where dichloromethane is used to prepare samples. This study underscores the solvent′s role in achieving high resolution and detection limits in clinical diagnostics (He J et al., 2024).

Features and Benefits

ACS solvents meet or exceed the high standards of the American Chemical Society (ACS) ,with test specifications that are specialized to every compound. According to the American Chemical Society, ACS reagent grade implies that it is a substance of sufficient purity to be used in most chemical analyses or reactions.

General description

Our premium ACS solvents are ideal for routine chemical synthesis, drying, purification, and critical labware cleaning. They meet or exceed the rigorous standards of the American Chemical Society (ACS), ensuring high-quality results for your research needs.

Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.

Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.

Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system

保管分類

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 2

flash_point_f

does not flash

flash_point_c

does not flash


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

第一種指定化学物質

prtr

名称等を表示すべき危険物及び有害物

ishl_indicated

名称等を通知すべき危険物及び有害物

ishl_notified

320269-BULK: + 320269-VAR: + 320269-1L:4548173240817 + 320269-4X4L:4548173240800 + 320269-4L:4548173240824

jan


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文書ライブラリにアクセスする

Helen Harrington et al.
Journal of visualized experiments : JoVE, (81)(81), e50608-e50608 (2013-12-05)
Culturing cells in 3D on appropriate scaffolds is thought to better mimic the in vivo microenvironment and increase cell-cell interactions. The resulting 3D cellular construct can often be more relevant to studying the molecular events and cell-cell interactions than similar
Effect of activated carbon content in TiO2-loaded activated carbon on photodegradation behaviors of dichloromethane.
Torimoto T, et al.
Journal of Photochemistry and Photobiology A: Chemistry, 103(1), 153-157 (1997)
Dipyridine-chromium (VI) oxide oxidation of alcohols in dichloromethane.
Collins JC, et al.
Tetrahedron Letters, 9(30), 3363-3366 (1968)
Myat Noe Hsu et al.
Biomicrofluidics, 9(5), 052601-052601 (2015-04-01)
The poor solubility of many newly discovered drugs has resulted in numerous challenges for the time-controlled release of therapeutics. In this study, an advanced drug delivery platform to encapsulate and deliver hydrophobic drugs, consisting of poly (lactic-co-glycolic acid) (PLGA) nanoparticles
Angharad M Roberts et al.
Science translational medicine, 7(270), 270ra6-270ra6 (2015-01-16)
The recent discovery of heterozygous human mutations that truncate full-length titin (TTN, an abundant structural, sensory, and signaling filament in muscle) as a common cause of end-stage dilated cardiomyopathy (DCM) promises new prospects for improving heart failure management. However, realization

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