395B
過ヨウ素酸シッフ（PAS）染色システム
Application
標準手順と電子レンジ用手順が添付されています。
過ヨウ素酸で処理すると、グリコールがアルデヒドに酸化されます。シッフ試薬(パラローズアニリンとメタ重亜硫酸ナトリウムの混合物)との反応後、 パラローズアニリン付加物が放出され、これがグリコールを含有する細胞成分をピンク～赤色に染色します。PAS法によって呈色する細胞成分は、グリコーゲン、真菌壁、基底膜、特定の上皮スルホムチンとシアロムチン、中性粘液物質、甲状腺の膠様物質、下垂体中間部です。
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Danger
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 1B - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1 - STOT RE 2 Oral
target_organs
Kidney
保管分類
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Angela C Nolin et al.
American journal of physiology. Renal physiology, 311(6), F1271-F1279 (2016-09-02)
Proteinuria is a major risk factor for chronic kidney disease progression. Furthermore, exposure of proximal tubular epithelial cells to excess albumin promotes tubular atrophy and fibrosis, key predictors of progressive organ dysfunction. However, the link between proteinuria and tubular damage
Nicolas Broguiere et al.
Advanced materials (Deerfield Beach, Fla.), 30(43), e1801621-e1801621 (2018-09-12)
Epithelial organoids are simplified models of organs grown in vitro from embryonic and adult stem cells. They are widely used to study organ development and disease, and enable drug screening in patient-derived primary tissues. Current protocols, however, rely on animal-
Ming Jiang et al.
Nature, 550(7677), 529-533 (2017-10-12)
In several organ systems, the transitional zone between different types of epithelium is a hotspot for pre-neoplastic metaplasia and malignancy, but the cells of origin for these metaplastic epithelia and subsequent malignancies remain unknown. In the case of Barrett's oesophagus
Roshane Francis et al.
Science advances, 5(12), eaax8898-eaax8898 (2019-12-18)
Transcription factors (TFs) are spatially and temporally regulated during gut organ specification. Although accumulating evidence shows aberrant reactivation of developmental programs in cancer, little is known about how TFs drive lineage specification in development and cancer. We first defined gastrointestinal
Satish Patel et al.
PloS one, 6(1), e15845-e15845 (2011-01-22)
Over-activity and elevated expression of glycogen synthase kinase-3 (GSK-3) has been implicated in the etiology of insulin resistance and Type 2 diabetes. Administration of specific GSK-3 inhibitors to diabetic or obese rodent models improves glycaemic control and insulin sensitivity. However
資料
Fungal stains remain an important tool in the histology laboratory's diagnostic arsenal for identifying infectious microorganisms.
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