42602
Propionyl-L-carnitine
≥94.0% (HPLC), suitable for LC/MS
別名:
(2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt, L-Carnitine propionyl ester, C3-Carnitine, Propanoyl-L-carnitine
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この商品について
実験式（ヒル表記法）:
C10H19NO4
CAS番号:
分子量:
217.26
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:
製品名
Propionyl-L-carnitine, ≥94.0% (HPLC)
Quality Level
assay
≥94.0% (HPLC)
form
powder or crystals
optical activity
[α]/D -23±3°, c = 1 in H2O
technique(s)
LC/MS: suitable
impurities
≤10% water (calcd. from elemental analysis)
color
white to off-white
storage temp.
2-8°C
SMILES string
[O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O
InChI
1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1
InChI key
UFAHZIUFPNSHSL-MRVPVSSYSA-N
General description
Propionyl-L-carnitine (PLC) is a short-chain fatty acid ester derivative of carnitine.
Application
Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Biochem/physiol Actions
Propionyl-L-carnitine (PLC) plays a key role in lipid and carbohydrate metabolism. It provides substrates to the ischemic muscle for energy production and ATP generation. PLC has the potential to treat severe peripheral arterial disease and chronic heart failure. It is present in high abundance in the urine of patients with methylmalonyl-CoA mutase (MUT) deficiency, together with methylmalonic acid. MUT is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA.
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保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable