50246
Poloxamer 407(微粒子)
別名:
ポリ(エチレングリコール)-block-ポリ(プロピレングリコール)-block-ポリ(エチレングリコール)
SMILES string
O2C(C2)C.O1CC1
InChI
1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
InChI key
RVGRUAULSDPKGF-UHFFFAOYSA-N
mol wt
~9840-14600 g/mol
composition
oxyethylene content, 71.5-74.9%
impurities
≤0.25% ethylene glycol and diethylene glycol
≤0.4% total ash
≤0.75% water
≤1 ppm ethylene oxide
≤2 ppm arsenic
≤20 ppm heavy metals
50-125 ppm butylhydroxytoluene
ign. residue
≤0.30%
color
APHA: ≤120
particle size distribution
, coeff var ≤10% (residue, No. 140 USS)
, coeff var ≤50% (residue, No. 270 USS)
pH
5.0-7.5(1:10)
5.0-7.5(1:40)
suitability
complies for Infrared spectrum
Quality Level
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関連するカテゴリー
Analysis Note
残留溶媒(GLC-HS)
1,4-ジオキサン ≤ 5 ppm、エチレングリコール ≤ 620 ppm(ランダムサンプルのみ検証済み)
1,4-ジオキサン ≤ 5 ppm、エチレングリコール ≤ 620 ppm(ランダムサンプルのみ検証済み)
Other Notes
平均分子量/質量9840～14600 g/mol、平均分子質量10000～14600 g/mol
Application
The Poloxamer 407 grades are poloxamers from the extensive line of Pluronic® block copolymers. They are widely used as a thickening agent and gel binder.
Legal Information
Pluronic is a registered trademark of BASF
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Xijun Zhang et al.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 31(6), 842-845 (2011-12-17)
This study examined the effect of P85 (a pluronic block copolymer) and microbubble (MB) ultrasound contrast agents under ultrasound irradiation on gene transfection and expression. The pEGFP plasmids that can encode enhanced green fluorescent protein (pEGFP) served as a report
Houjian Gong et al.
Langmuir : the ACS journal of surfaces and colloids, 28(38), 13590-13600 (2012-09-08)
The block polyethers PEO-PPO-ph-PPO-PEO (BPE) and PPO-PEO-ph-PEO-PPO (BEP) are synthesized by anionic polymerization using bisphenol A as initiator. Compared with Pluronic P123, the aggregation behaviors of BPE and BEP at an air/water interface are investigated by the surface tension and
Mi Mi Wan et al.
Journal of colloid and interface science, 377(1), 497-503 (2012-04-18)
New concept on the promotion of immobilization and catalytic activity of enzyme on mesoporous silica through template micelles is proposed and realized in this paper. Proper P123 templates are controllable retained in the as-synthesized SBA-15, not only to anchor the
Yanbin Guan et al.
Archives of pharmacal research, 34(10), 1719-1728 (2011-11-15)
The aim of the present study was to evaluate the effect of pluronic P123 (P123) and pluronic F127 (F127) on intestinal P-glycoprotein (P-gp) and cytochrome P450 3A using the specific substrates rhodamine-123 (R-123) and midazolam, respectively. Caco-2 cells and everted
Wanhua Feng et al.
Colloids and surfaces. B, Biointerfaces, 105, 43-50 (2013-01-29)
The interaction between bacteria and surfaces is central to many environmental, industrial and medical applications. Surfactants are commonly used in these applications and can potentially influence the bacterium/surface interaction. The effect of surfactants upon bacterial cell surface thermodynamic properties was
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