81357
ポリ(Glu, Tyr) ナトリウム塩
suitable for ligand binding assays, Mol wt 20,000-50,000
製品名
ポリ(Glu, Tyr) ナトリウム塩, mol wt 20,000-50,000, Glu:Tyr 4:1
form
powder
feed ratio
Glu:Tyr (4:1)
mol wt
20,000-50,000
technique(s)
ligand binding assay: suitable
color
white to off-white
storage temp.
−20°C
Quality Level
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関連するカテゴリー
Biochem/physiol Actions
Poly(Glu,Tyr) (poly(Glu,Tyr) 4:1 random copolymer) is used as a substrate for the evaluation of protein tyrosine kinase(s).
Poly(Glu,Tyr) 4:1 is a polyamino acid used in the manufacture of electrochemical biosensors for detection of reactions such as Fenton induced tyrosine oxidation.
Other Notes
ポリアミノ酸に関するさらに詳細な技術情報をお求めの場合は、ポリアミノ酸FAQをご覧下さい。
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
81357-250MG: + 81357-50MG: + 81357-BULK: + 81357-VAR:
jan
Masanobu Chiku et al.
Biosensors & bioelectronics, 26(1), 235-240 (2010-07-17)
In this report, we determined protein tyrosine kinase (PTKs) activity in human epidermoid carcinoma cells (A431) by employing a novel electrochemical method using boron-doped diamond (BDD) electrodes that enables the electrochemical oxidation of tyrosine (Tyr), phosphorylated Tyr (Tyr-P) and sulfated
Na Qu et al.
Biosensors & bioelectronics, 26(5), 2292-2296 (2010-11-03)
A simple and sensitive electrochemical biosensor was used to detect tyrosine oxidation induced by hydroxyl radicals generated by Fenton reaction (Fe(2+)/H(2)O(2)). Poly(glu, tyr) (4:1) peptides were immobilized on indium tin oxide (ITO) electrode surface via layer-by-layer assembly technique, and Os(bpy)(3)(2+)-mediated
Morten R Clausen et al.
Journal of agricultural and food chemistry, 56(18), 8692-8698 (2008-09-02)
Oxidation of 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) by lactoperoxidase was found to be inhibited by tyrosine-containing random amino acid copolymers but not by tyrosine. Both electrostatic effects and polymer size were found to be important by comparison of negatively and positively charged copolymers
D M Williams et al.
The Journal of biological chemistry, 275(49), 38127-38130 (2000-09-28)
Protein-tyrosine kinases contain a catalytic loop Arg residue located either two or four positions downstream of a highly conserved Asp residue. In this study, the role of this Arg (Arg-318) in the protein-tyrosine kinase C-terminal Src kinase (Csk) was investigated.
Edit Varkondi et al.
Journal of receptor and signal transduction research, 25(1), 45-56 (2005-06-18)
Receptor tyrosine kinases (PTKs) play key roles in the pathogenesis of numerous human diseases, including cancer, and therefore PTK inhibitors are currently under intense investigation as potential drug candidates. PTK inhibitor screening data are, however, poorly comparable because of the
資料
Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.
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