A2010
Nα-アセチル-L-リシン
≥98% (TLC), suitable for ligand binding assays
別名:
N2-acetyl-L-lysine
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この商品について
化学式:
H2N(CH2)4CH(NHCOCH3)CO2H
CAS番号:
分子量:
188.22
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
EC Number:
217-747-5
MDL number:
製品名
Nα-アセチル-L-リシン,
SMILES string
CC(=O)N[C@@H](CCCCN)C(O)=O
InChI
1S/C8H16N2O3/c1-6(11)10-7(8(12)13)4-2-3-5-9/h7H,2-5,9H2,1H3,(H,10,11)(H,12,13)/t7-/m0/s1
InChI key
VEYYWZRYIYDQJM-ZETCQYMHSA-N
assay
≥98% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
color
colorless to white
mp
256-258 °C (dec.) (lit.)
storage temp.
−20°C
Quality Level
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関連するカテゴリー
Application
Nα-アセチル-L-リジンは、本物のα-アミノアジピン酸セミアルデヒド(AAS)-p-アミノ安息香酸（ABA）の合成のためのリシルオキシダーゼの基質として使用されています。これは、4,4'-メチレンジフェニルジイソシアネート（MDI）のアミノ酸付加物の合成に使用される場合があります。
Biochem/physiol Actions
Nα-アセチル-L-リジンは、タンパク質性α アミノ酸L-リジンの生物学的に利用可能なN末端キャップ型です。Nα-アセチル-L-リジンは、リシルオキシダーゼの研究と特性解析に使用される基質です。
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
N Murata-Kamiya et al.
Nucleic acids research, 29(16), 3433-3438 (2001-08-16)
Methylglyoxal, a known endogenous and environmental mutagen, is a reactive alpha-ketoaldehyde that can modify both DNA and proteins. To investigate the possibility that methylglyoxal induces a crosslink between DNA and DNA polymerase, we treated a 'primed template' DNA and the
Jing Bi et al.
Emerging microbes & infections, 7(1), 108-108 (2018-06-15)
The DosR regulon is believed to be a key factor in latency adaptation of Mycobacterium tuberculosis and is strongly induced by multiple stresses, including hypoxia. Previous studies have revealed reversible acetylation of the conserved core DNA-binding lysine residue 182 (K182)
Osama Abo Alrob et al.
Cardiovascular research, 103(4), 485-497 (2014-06-27)
Lysine acetylation is a novel post-translational pathway that regulates the activities of enzymes involved in both fatty acid and glucose metabolism. We examined whether lysine acetylation controls heart glucose and fatty acid oxidation in high-fat diet (HFD) obese and SIRT3
Yael Belo et al.
Biochimica et biophysica acta. General subjects, 1863(9), 1343-1350 (2019-06-07)
The signal transducer and activator of transcription 3 (STAT3) protein is activated by phosphorylation of a specific tyrosine residue (Tyr705) in response to various extracellular signals. STAT3 activity was also found to be regulated by acetylation of Lys685. However, the
K Seyssel et al.
The Journal of clinical endocrinology and metabolism, 99(7), E1254-E1262 (2014-04-02)
The aim of this study was to evaluate the regulation of the fuel partitioning and energy metabolism in skeletal muscle during lipid overfeeding in healthy men. Design/Participants/Intervention: Thirty-nine healthy volunteers were overfed for 56 days with a high-fat diet (3180
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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