A5508
アデノシン 5′-ホスホ硫酸 ナトリウム塩
≥85%, synthetic (organic), powder
別名:
APS
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この商品について
実験式（ヒル表記法）:
C10H14N5O10PS
CAS番号:
分子量:
427.28
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
MDL number:
製品名
アデノシン 5′-ホスホ硫酸 ナトリウム塩, ≥85%
Quality Level
SMILES string
[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OS(O)(=O)=O)C(O)C3O
InChI
1S/C10H14N5O10PS.Na.H/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-26(18,19)25-27(20,21)22;;/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H2,11,12,13)(H,20,21,22);;
InChI key
KLZADYTZAADWRW-UHFFFAOYSA-N
biological source
synthetic (organic)
assay
≥85%
form
powder
solubility
water: 50 mg/mL, clear to hazy, colorless to light yellow
documentation
see Safety & Documentation for available documents
food allergen
no known allergens
shipped in
dry ice
storage temp.
−20°C
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Application
アデノシン5′-ホスホ硫酸ナトリウム塩は、アデノシン三リン酸（ATP）およびピロホスファートの定量のために、酵素結合バイオルミネセンスアッセイに使用されています。
Biochem/physiol Actions
アデノシン5′-ホスホ硫酸（APS）は、ホタルルシフェラーゼATP発光アッセイおよび他のピロホスファート酸再生依存性検出アッセイにおいてアデノシン三リン酸（ATP）スルフリラーゼの基質として使用され、PP(i)リサイクルループを完了させATPを指数関数的に増幅させます。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment
Villa BR, et al.
Circulation, 127(24), 2442-2451 (2013)
Novel bioluminescent assay of alkaline phosphatase using adenosine-3?-phosphate-5?-phosphosulfate as substrate and the luciferin-luciferase reaction and its application
Arakawa H, et al.
Analytical biochemistry, 314(2), 206-211 (2003)
Fumika Mi-Ichi et al.
PLoS neglected tropical diseases, 13(8), e0007633-e0007633 (2019-08-20)
Amoebiasis, caused by Entamoeba histolytica infection, is a global public health problem. However, available drugs to treat amoebiasis are currently limited, and no effective vaccine exists. Therefore, development of new preventive measures against amoebiasis is urgently needed. Here, to develop
Momoko Horikoshi et al.
PLoS genetics, 11(7), e1005230-e1005230 (2015-07-02)
Reference panels from the 1000 Genomes (1000G) Project Consortium provide near complete coverage of common and low-frequency genetic variation with minor allele frequency ≥0.5% across European ancestry populations. Within the European Network for Genetic and Genomic Epidemiology (ENGAGE) Consortium, we
Kenji Tanimura et al.
Blood, 125(18), 2835-2844 (2015-03-04)
Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by thrombosis and/or pregnancy complications. β2-glycoprotein I (β2GPI) complexed with phospholipid is recognized as a major target for autoantibodies in APS; however, less than half the patients with clinical manifestations of APS
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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