B3398
モノクロナール抗ヒトIgG2−ビオチン マウス宿主抗体
clone HP-6014, purified from hybridoma cell culture
別名:
モノクロナール抗ヒトIgG2
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この商品について
NACRES:
NA.46
UNSPSC Code:
12352203
Conjugate:
biotin conjugate
Clone:
HP-6014, monoclonal
Application:
ELISA (d)
Citations:
14
biological source
mouse
Quality Level
conjugate
biotin conjugate
antibody form
purified from hybridoma cell culture
antibody product type
secondary antibodies
clone
HP-6014, monoclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
direct ELISA: 1:30,000
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
Monoclonal Anti-Human IgG2 (mouse IgG1 isotype) is derived from the hybridoma (HP-60141 ) produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. IgG is the most abundant serum immunoglobulins of the immune system. IgG2 is a subtype of IgG. IgG is secreted by B cells and is found in blood and extracellular fluids.
Application
Monoclonal Anti-Human IgG2−Biotin antibody produced in mouse has been used in indirect enzyme linked immunosorbent assay (ELISA) and immunoblot.
Biochem/physiol Actions
本抗体は、ヒトIgG2に特異的であり、他のIgGサブクラスには反応しません。このクローンは、IUIS/WHOの研究によって、最も幅広く応用されるIgG2特異的モノクローナル抗体として選ばれています。
IgG provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Low IgG2 levels were found in patients with systemic lupus erythematosus (SLE) and juvenile diabetes melitus.
Physical form
0.01 M PBS溶液(pH 7.4, 1% BSA, 15 mMアジ化ナトリウム含有)
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
B3398-VAR: + B3398-.2ML: + B3398-.5ML: + B3398-BULK:
jan
Placental transfer of IgG subclasses in a Japanese population
Hashira S, et al.
Pediatrics International, 42, 337-342 (2000)
Alberts B, et al.
Molecular biology of the Cell. 4th Edition., 42, 337-342 (2002)
Immunoglobulin subclass deficiency
Hanson L A, et al.
The Pediatric Infectious Disease Journal, 7, 7-21 (1988)
Elana R Shaw et al.
Current protocols, 2(8), e511-e511 (2022-08-18)
Autoantibodies (autoAbs) that neutralize type 1 interferons (T1IFNs) are a major risk factor associated with developing critical COVID-19 disease and are most commonly found in individuals over age 70 and in patients with genetic or acquired thymic defects. Swift identification
Marianna Spatola et al.
Neurology, 95(22), e3012-e3025 (2020-09-16)
To clinically characterize patients with anti-metabotropic glutamate receptor (mGluR) 1 encephalitis, to identify prognostic factors, and to study the immunoglobulin G (IgG) subclasses and effects of antibodies on neuronal mGluR1 clusters. Clinical information on new and previously reported patients was
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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