C102
8-シクロペンチル-1,3-ジメチルキサンチン
≥98% (HPLC), powder
別名:
8-シクロペンチルテオフィリン, CPT
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この商品について
実験式（ヒル表記法）:
C12H16N4O2
CAS番号:
分子量:
248.28
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
製品名
8-シクロペンチル-1,3-ジメチルキサンチン, ≥98% (HPLC), powder
InChI key
SCVHFRLUNIOSGI-UHFFFAOYSA-N
SMILES string
CN1C(=O)N(C)c2nc([nH]c2C1=O)C3CCCC3
InChI
1S/C12H16N4O2/c1-15-10-8(11(17)16(2)12(15)18)13-9(14-10)7-5-3-4-6-7/h7H,3-6H2,1-2H3,(H,13,14)
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
H2O: slightly soluble <0.28 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.77 mg/mL
DMSO: ~16 mg/mL at 60 °C
0.1 M NaOH: soluble
Quality Level
Gene Information
human ... ADORA1(134)
Biochem/physiol Actions
A1アデノシンレセプタ-の選択的アンタゴニストです。
Features and Benefits
This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Nucleic acids research, 44(17), 8261-8271 (2016-06-30)
Small interfering RNAs (siRNAs) defend the organism against harmful transcripts from exogenous (e.g. viral) or endogenous (e.g. transposons) sources. Recent publications describe the production of siRNAs induced by DNA double-strand breaks (DSB) in Neurospora crassa, Arabidopsis thaliana, Drosophila melanogaster and
Trudy Rebbeck et al.
Physical therapy, 95(11), 1536-1546 (2015-05-30)
Correlations between clinical and quantitative measures of pain sensitivity are poor, making it difficult for clinicians to detect people with pain sensitivity. Clinical detection of pain sensitivity is important because these people have a different prognosis and may require different
Harald Schuhwerk et al.
Nucleic acids research, 45(19), 11174-11192 (2017-10-05)
One of the fastest cellular responses to genotoxic stress is the formation of poly(ADP-ribose) polymers (PAR) by poly(ADP-ribose)polymerase 1 (PARP1, or ARTD1). PARP1 and its enzymatic product PAR regulate diverse biological processes, such as DNA repair, chromatin remodeling, transcription and
Huihui Chen et al.
Nature communications, 9(1), 3209-3209 (2018-08-12)
Glaucoma is the most prevalent neurodegenerative disease and a leading cause of blindness worldwide. The mechanisms causing glaucomatous neurodegeneration are not fully understood. Here we show, using mice deficient in T and/or B cells and adoptive cell transfer, that transient
Hiro Sato et al.
Nature communications, 8(1), 1751-1751 (2017-11-25)
Accumulating evidence suggests that exogenous cellular stress induces PD-L1 upregulation in cancer. A DNA double-strand break (DSB) is the most critical type of genotoxic stress, but the involvement of DSB repair in PD-L1 expression has not been investigated. Here we
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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