C2538
カルボプラチン
DNA cross-linking agent, powder
別名:
cis-ジアンミン(1,1-シクロブタンジカルボキシラト)プラチナ
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この商品について
製品名
カルボプラチン,
form
powder
Quality Level
antibiotic activity spectrum
neoplastics
originator
Bristol-Myers Squibb
SMILES string
N.N.O=C1O[Pt]OC(=O)C12CCC2
InChI
1S/C6H8O4.2H3N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H3;/q;;;+2/p-2
InChI key
OLESAACUTLOWQZ-UHFFFAOYSA-L
General description
Application
- 化学療法誘導性の血小板減少症のマウスモデル、および治療
- 結腸直腸癌細胞のラージサブセットにおける細胞死の誘導
- 細胞増殖および化学受容性の評価
- 細胞増殖抑制のポジティブコントロール
Biochem/physiol Actions
Features and Benefits
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signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Muta. 1B - Repr. 1B - Resp. Sens. 1 - Skin Sens. 1
保管分類
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
資料
DNA damage and repair mechanism is vital for maintaining DNA integrity. Damage to cellular DNA is involved in mutagenesis, the development of cancer among others.
Cell cycle phases (G1, S, G2, M) regulate cell growth, DNA replication, and division in proliferating cells.
Apoptosis regulation involves multiple pathways and molecules for cellular homeostasis.