I2512
ヨード酢酸ナトリウム
powder, ≥98%
別名:
ヨード酢酸 ナトリウム塩
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この商品について
化学式:
ICH2COONa
CAS番号:
分子量:
207.93
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
206-165-7
MDL number:
Beilstein/REAXYS Number:
4009322
製品名
ヨード酢酸ナトリウム, ≥98%
InChI
1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1
InChI key
AGDSCTQQXMDDCV-UHFFFAOYSA-M
SMILES string
[Na+].[O-]C(=O)CI
biological source
synthetic (organic)
assay
≥98%
form
powder
mp
208 °C (dec.) (lit.)
solubility
H2O: 100 mg/mL
storage temp.
−20°C
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Application
タンパク質のシステイン残基の修飾試薬。タンパク質配列解析(ウシインスリンの配列解析におけるサンガー法による解析を含む)で、-SH側鎖の酸化防止に使用されます。
タンパク質のシステイン残基の修飾試薬。変形性関節症のヒトにおける症状と組織病理とを再現する動物モデル系を誘発するために使用されます。
タンパク質のシステイン残基を修飾する試薬です。
Biochem/physiol Actions
軟骨保護剤および画像診断法の検討を目的としてラットに変形性関節症様の病変と機能障害を誘発させるために用いられます。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1B
保管分類
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
406.4 °F
flash_point_c
208 °C
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
C Guingamp et al.
Arthritis and rheumatism, 40(9), 1670-1679 (1997-10-27)
To characterize the dose-responsiveness of morphologic and biochemical chondral changes relative to mobility in mono-iodoacetate (MIA)-induced osteoarthritis (OA) in rats. Rat mobility was assessed by biotelemetry. Articular lesions were characterized by macroscopic and histologic examinations. Cartilage proteoglycan metabolism was evaluated
Roberto E Guzman et al.
Toxicologic pathology, 31(6), 619-624 (2003-10-31)
Osteoarthritis (OA) is a degenerative joint disease characterized by joint pain and a progressive loss of articular cartilage. Studies to elucidate the pathophysiology of OA have been hampered by the lack of a rapid, reproducible animal model that mimics both
Matilde Tschon et al.
Cells, 9(7) (2020-07-02)
The purpose of this study was to verify the efficacy of a single intra-articular (i.a.) injection of a hyaluronic acid-chitlac (HY-CTL) enriched with two low dosages of triamcinolone acetonide (TA, 2.0 mg/mL and 4.5 mg/mL), in comparison with HY-CTL alone
Ikufumi Takahashi et al.
PloS one, 13(4), e0196625-e0196625 (2018-04-27)
This study aimed to investigate the histopathological changes in the patellofemoral joint using a rat model of osteoarthritis that was induced using monosodium iodoacetate, and to establish a novel model of patellofemoral osteoarthritis in a rat model using histopathological analysis.
Hyung Jin Lim et al.
Food science & nutrition, 8(12), 6550-6556 (2020-12-15)
In Asia, Vigna angularis (azuki bean) has been used as a traditional medicine to treat various diseases because of its biological properties. Osteoarthritis (OA) and osteoporosis (OP) are common regenerative bone diseases that are characterized by deterioration of joint and
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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