リポポリサッカリド Pseudomonas aeruginosa10（緑膿菌）由来

リポ多糖類（LPS）はグラム陰性細菌の細胞壁に特徴的な成分です。LPS とその脂質A成分は、一般的な病原体関連分子パターン（PAMP）を認識する Toll 様受容体タンパク質ファミリーに属する Toll 様受容体 4（TLR4）を介して自然免疫系の細胞を刺激します。

Lipopolysaccharides (LPS) are localized in the outer layer of the membrane and are, in noncapsulated strains, exposed on the cell surface. They contribute to the integrity of the outer membrane, and protect the cell against the action of bile salts and lipophilic antibiotics.

This product is TCA extracted from Pseudomonas aeruginosa serotype 10. The source strain is ATCC 27316.

To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

The product is soluble in water (5 mg/ml) or cell culture medium (1 mg/ml) yielding a hazy, faint yellow solution. A more concentrated, though still hazy, solution (20 mg/ml) has been achieved in aqueous saline after vortexing and warming to 70-80 ^oC. Lipopolysaccharides are molecules that form micelles in every solvent. Hazy solutions are observed in water and phosphate buffered saline. Organic solvents do not give clearer solutions. Methanol yields a turbid suspension with floaters, while water yields a homogeneously hazy solution.