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Merck

M2172

1-チオグリセロール

BioXtra, ≥97%

別名:

α-チオグリセロール, α-モノチオグリセロール, 3-メルカプト-1,2-プロパンジオール

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この商品について

化学式:
HSCH2CH(OH)CH2OH
CAS番号:
96-27-5
分子量:
108.16
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
24896709
EC Number:
202-495-0
Beilstein/REAXYS Number:
1732046
MDL number:
MFCD00004879

主要文書

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製品名

1-チオグリセロール, BioXtra, ≥97%

InChI key

PJUIMOJAAPLTRJ-UHFFFAOYSA-N

InChI

1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2

SMILES string

OCC(O)CS

product line

BioXtra

assay

≥97%

form

liquid

impurities

≤0.0005% Phosphorus (P)

ign. residue

≤0.1%

refractive index

n20/D 1.527 (lit.)

bp

118 °C/5 mmHg (lit.)

density

1.25 g/mL at 25 °C (lit.)

cation traces

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.02%
Pb: ≤0.001%
Zn: ≤0.0005%

storage temp.

2-8°C

Quality Level

200

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関連するカテゴリー

Application

It has been used in a study to assess thiol-sensitive genes and promoters of Escherichia coli.

General description

1-Thioglycerol stimulates the synthesis of porphyrin in aerobically growing Escherichia coli. It is an inhibitor of glycerol kinase activity in vitro and in situ.

Preparation Note

This product is miscible in ethanol (1 ml/ml, 50%, v/v), yielding a clear, colorless solution. It is also miscible in water (0.1 M).

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Skin Irrit. 2 - Skin Sens. 1B

保管分類

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

210.2 °F - closed cup

flash_point_c

99 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

最新バージョンのいずれかを選択してください：

試験成績書（COA）

Lot/Batch Number
SLCJ5984
SLCJ5981
SLCJ1634
SLCH1247
SLCC7335

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以前この製品を購入いただいたことがある場合

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W K Seltzer et al.
Life sciences, 39(16), 1417-1424 (1986-10-20)
The infantile form of glycerol kinase (GK) deficiency (McKusick No. 30703) (1) is characterized by adrenal cortical insufficiency, adrenal hypoplasia and developmental delay. The underlying biochemical mechanism(s) responsible for the observed clinical presentations are undetermined. Pursuant to our examination of
G T Javor
Journal of bacteriology, 171(10), 5607-5613 (1989-10-01)
The effect of 1-thioglycerol on the expression of genes of Escherichia coli was investigated. Pulse-labeled proteins from aerobically growing, 1-thioglycerol-treated E. coli were separated by two-dimensional gel electrophoresis, and their radioactivities were compared with those of identical proteins from nontreated
G T Javor et al.
Journal of bacteriology, 170(7), 3291-3293 (1988-07-01)
Mu dX(lac) insertion mutants of Escherichia coli CSH50 in which the expression of the lacZ gene was sensitive to the presence of exogenous 1-thioglycerol or dithiothreitol were isolated. Both stimulatory and inhibitory mutants were found. The existence of several thiol-sensitive
P Tengvall et al.
Biomaterials, 17(10), 1001-1007 (1996-05-01)
Thiol-modified surfaces are chemically well defined and suited for surface biological model experiments and biomaterials research. 3-Mercapto-1,2-propanediol (mercaptoglycerol, MG), immobilized on gold, spontaneously binds immunoglobulins from human serum and activates the complement system. The surface-bound complement factors were detected by
Jonas Wetterö et al.
Biomaterials, 23(4), 981-991 (2002-01-17)
Since the realization of a complement activation capacity by artificial surfaces upon contact with blood, a common belief has evolved that charged nucleophilic surface groups such as amine (-NH2) and hydroxyl (-OH) react with and eventually bind to the internal
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