M2696
メチラポン
≥98% (HPLC), glucocorticoid synthesis inhibitor, solid
別名:
2-メチル-1,2-ジ-3-ピリジル-1-プロパノン, Su-4885, メチラポン
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この商品について
実験式（ヒル表記法）:
C14H14N2O
CAS番号:
分子量:
226.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
200-206-2
MDL number:
Beilstein/REAXYS Number:
163023
製品名
メチラポン, ≥98% (HPLC), solid
InChI
1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3
SMILES string
CC(C)(c1cccnc1)C(=O)c2cccnc2
InChI key
FJLBFSROUSIWMA-UHFFFAOYSA-N
sterility
non-sterile
assay
≥98% (HPLC)
form
solid
technique(s)
toxicology assay: suitable
mp
52-55 °C (lit.)
solubility
H2O: <2 mg/mL
DMSO: >20 mg/mL
originator
Novartis
shipped in
ambient
storage temp.
room temp
Quality Level
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Biochem/physiol Actions
メチラポンはグルココルチコイド合成阻害剤です。ストレスに対する副腎機能評価や下垂体機能の評価におけるスタンダ-ドとなっています。メチラポンは、グルココルチコイド合成阻害剤として作用するのに加え、チトクロムP450を介したプロスタグランジンω/ω-1ヒドロキシラ-ゼ活性も阻害し、学習や記憶を妨げます。睡眠時の脳波を活性化し、デルタ睡眠を量的に大きく減少させることが示されています。
Features and Benefits
This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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