製品名
マッコイ5A培地, Modified, with L-glutamine and sodium bicarbonate, liquid, sterile-filtered, suitable for cell culture
sterility
sterile-filtered
form
liquid
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
components
NaHCO3: 2.2 g/L
L-glutamine: 0.21 g/L
phenol red: 0.011 g/L
glucose: 3.0 g/L (Dextro)
shipped in
ambient
storage temp.
2-8°C
Quality Level
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関連するカテゴリー
Application
McCoy′ 5A培地は、以下の用途に使用されています:
- HCT-116細胞の培養
- 淡明細胞型腎細胞癌(ccRCC)細胞Caki-1の培養
- in vitro細胞研究のためのヒト骨肉腫Saos-2細胞株の維持と培養
Biochem/physiol Actions
マッコイ5A培地は、もともとBMEに含まれるアミノ酸の改変により肝臓がん細胞を維持するように開発されました。′ この処方は、骨髄、皮膚、歯肉、腎臓、網、副腎、肺、脾臓、ラット胚、およびその他の細胞型の初代培養の増殖を維持するためにも使用されています。
General description
ノビコフ肝癌細胞in vitro培養のアミノ酸要件は、McCoyらが報告しました。これらの実験は基礎培地5Aを用いて行われ、基礎培地はその後改変されてMcCoy′ 5A培地が作られました。
保管分類
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Aleksandr Ianevski et al.
Cancers, 12(6) (2020-07-08)
The evidence that pan-Bcl-2 or Bcl-xL-specific inhibitors prematurely kill virus-infected or RNA/DNA-transfected cells provides rationale for investigating these apoptotic inducers further. We hypothesized that not only invasive RNA or DNA (biological factors) but also DNA/RNA-damaging chemical or physical factors could
Nengquan Sheng et al.
Cancer medicine, 6(6), 1331-1340 (2017-04-26)
MicroRNA-145 (miR-145), as a tumor-suppressive miRNA, has been demonstrated down-regulated in colorectal cancer (CRC) cells, and could inhibit CRC cells growth. However, the molecular pathway in which miR-145 modulates CRC malignant transformation has not been fully revealed. Here, we reported
Qiao Zhang et al.
Oncotarget, 8(65), 109043-109060 (2018-01-10)
Ectopic Glucose 6-phosphate dehydrogenase (G6PD) expression plays important role in tumor cell metabolic reprogramming and results in poor prognosis of multiple malignancies. Our previous study indicated that G6PD is overexpressed in clear cell renal cell carcinoma (ccRCC), the most common
Alison Roth et al.
Nature communications, 9(1), 1837-1837 (2018-05-11)
Malaria liver stages represent an ideal therapeutic target with a bottleneck in parasite load and reduced clinical symptoms; however, current in vitro pre-erythrocytic (PE) models for Plasmodium vivax and P. falciparum lack the efficiency necessary for rapid identification and effective
Xiangyu Li et al.
iScience, 24(7), 102722-102722 (2021-07-15)
Clear cell renal cell carcinoma (ccRCC) is the most common histological type of kidney cancer and has high heterogeneity. Stratification of ccRCC is important since distinct subtypes differ in prognosis and treatment. Here, we applied a systems biology approach to
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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