N3905
ナイカルバジン
別名:
N,N′-ビス(4-ニトロフェニル)ウレアと 4,6-ジメチル-2-ピリミジノンの化合物
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この商品について
実験式（ヒル表記法）:
C13H10N4O5 · C6H8N2O
CAS番号:
分子量:
426.38
NACRES:
NA.85
PubChem Substance ID:
UNSPSC Code:
51102829
EC Number:
206-359-1
MDL number:
InChI key
UKHWDRMMMYWSFL-UHFFFAOYSA-N
InChI
1S/C13H10N4O5.C6H8N2O/c18-13(14-9-1-5-11(6-2-9)16(19)20)15-10-3-7-12(8-4-10)17(21)22;1-4-3-5(2)8-6(9)7-4/h1-8H,(H2,14,15,18);3H,1-2H3,(H,7,8,9)
SMILES string
Cc1cc(C)nc(O)n1.[O-][N+](=O)c2ccc(NC(=O)Nc3ccc(cc3)[N+]([O-])=O)cc2
form
powder
antibiotic activity spectrum
parasites
mode of action
cell membrane | interferes
Quality Level
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関連するカテゴリー
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
Application
Nicarbazin is a coccidiostat (antiprotozoal agent) in the poultry industry and is a contraceptive for resident Canada geese and waterfowl. It is used to study avian reproduction and is used to interfere with the formation of the vitelline (yolk) membrane in bird eggs. It has been used to study how delivery method can effect plasma levels of 4,4′-dinitrocarbanilide (DNC), which is the active anticoccidial component of Nicarbazin.
Biochem/physiol Actions
Nicarbazin affects avian reproduction by reducing egg production, egg weight, and egg hatchability. The mechanism of action of Nicarbazin is unknown.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
保管分類
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
N3905-100G: + N3905-VAR: + N3905-BULK: + N3905-100G-PW:
jan
Martin Danaher et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 25(1), 32-40 (2007-10-25)
A survey was carried out on the occurrence of dinitrocarbanilide (DNC), the marker residue for nicarbazin, in poultry produced in Ireland during 2002-2004. Liver (n = 736) and breast muscle samples (n = 342) were tested. DNC residues were found
V Gaudin et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(23), 2358-2362 (2009-04-07)
Nicarbazin, a coccidiostat, is used as a feed additive in poultry but not in laying hens. Feed contamination may however occur resulting in residues being present in eggs. As a Maximum Residue Limit (MRL) does not exist for nicarbazin residues
Katrina Campbell et al.
Journal of agricultural and food chemistry, 55(6), 2497-2503 (2007-02-27)
Concentrations of the coccidiostat nicarbazin as low as 2 mg/kg in feed can result in violative drug residues arising in poultry liver. A lateral flow device (LFD) was developed for the detection of contaminating concentrations of nicarbazin following solvent extraction
G F Mathis et al.
Veterinary parasitology, 121(1-2), 1-9 (2004-04-28)
A 56-day floor pen study was conducted to determine the appropriate time to administer toltrazuril (Baycox) (TOL) for control of coccidiosis in broiler chickens. Litter was seeded with field strains of Eimeria acervulina, Eimeria maxima and Eimeria tenella. On Days
A-C Huet et al.
Food additives and contaminants, 22(2), 128-134 (2005-04-13)
Nicarbazin and halofuginone have been widely used as coccidiostats for the prevention and treatment of coccidiosis in poultry. It has been shown that accidental cross-contamination of feed can lead to residues of these compounds in eggs and/or muscle. This paper
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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