O5507
共役リノール酸
別名:
CLA, 複合オクタデカジエン酸
Biochem/physiol Actions
乳腺、皮膚、大腸での発がんおよび腫瘍細胞増殖に対する強力な阻害剤です。bFGF誘導性の内皮細胞増殖を阻害します。
General description
cis-およびtrans-の9,11-および-10,12-オクタデカジエン酸の混合物です。アイソマ-混合比はロットによって異なります。
Application
- A targeted nanomodulator capable of manipulating tumor microenvironment against metastasis.: The paper discusses the development of a targeted nanomodulator, including conjugated linoleic acid, to manipulate the tumor microenvironment and inhibit metastasis. The findings suggest significant potential for improved cancer treatments (Tian et al., 2022).
- Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.: The research focuses on hyaluronic acid-modified nanoparticles using linoleic acid-conjugated chitosan for the codelivery of miR34a and doxorubicin. This approach aims to overcome drug resistance in breast cancer treatments (Yang et al., 2022).
保管分類
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Eun-Joung Moon et al.
Oncology reports, 10(3), 617-621 (2003-04-10)
Conjugated linoleic acid (CLA) is a potent inhibitor of mammary carcinogenesis. Cancer cells produce various angiogenic factors which stimulate host vascular endothelial cell mitogenesis and chemotaxis for their growth and metastasis. Basic fibroblast growth factor (bFGF) is a potent angiogenic
Martha A Belury
The Journal of nutrition, 132(10), 2995-2998 (2002-10-09)
Conjugated linoleic acid (CLA) is composed of positional and stereoisomers of octadecadienoate (18:2); it is found in foods derived from ruminants (beef and lamb as well as dairy products from these sources). When a mixture of isomers is fed to
Atique A Behan et al.
Animals : an open access journal from MDPI, 9(7) (2019-07-03)
Rumen protected fats (RPF) are known to improve animal performance without affecting rumen metabolism in sheep. However, comparative effects of prilled fat, prilled fat with lecithin and calcium soap have not been fully studied. Hence this experiment was planned using
E Linda R Sheldrick et al.
The Biochemical journal, 406(1), 175-183 (2007-05-23)
Arachidonic acid is a potential paracrine agent released by the uterine endometrial epithelium to induce PTGS2 [PG (prostaglandin)-endoperoxide synthase 2] in the stroma. In the present study, bovine endometrial stromal cells were used to determine whether PTGS2 is induced by
Daeun Lee et al.
Archives of pharmacal research, 43(4), 449-461 (2020-04-03)
Schizophyllan (SPG), produced by Schizophyllum commune, is an exopolysaccharide with multiple academic and commercial uses, including in the food industry and for various medical functions. We previously demonstrated that SPG conjugated with c-Src peptide exerted a significant therapeutic effect on
資料
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
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