P9607
Anti-Potassium Channel Kv2.1 (DRK1) antibody produced in rabbit
IgG fraction of antiserum, lyophilized powder
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この商品について
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, IP, WB CL
Citations:
6
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
rat
technique(s)
immunocytochemistry: suitable, immunoprecipitation (IP): suitable, western blot (chemiluminescent): 1:250-1:500
UniProt accession no.
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... KCNB1(3745)
mouse ... Kcnb1(16500)
rat ... Kcnb1(25736)
関連するカテゴリー
Immunogen
synthetic peptide corresponding to amino acids 837-853 of rat potassium channel Kv2.1 (with an additional N-terminal cysteine and tyrosine).The epitope is identical in mouse and rat and highly homologous in human and pig.
Physical form
Lyophilized at ∼1 mg/ml from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, 5% sucrose and 0.05% sodium azide.
Preparation Note
Protein A purified.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
J S Trimmer
Proceedings of the National Academy of Sciences of the United States of America, 88(23), 10764-10768 (1991-12-01)
Antibodies specific for the drk1 polypeptide were used to characterize the corresponding protein in rat brain. Recombinant and synthetic immunogens containing fragments of the drk1 polypeptide were produced. Antibodies raised to these immunogens display monospecific reactions with the same 130-kDa
G Shi et al.
The Journal of biological chemistry, 269(37), 23204-23211 (1994-09-16)
We have transiently expressed the rat Kv2.1 K+ channel polypeptide (pKv2.1) at high levels by transfection of mammalian COS-1 cells. Kv2.1-transfected cells express a molecular mass of 108 kDa pKv2.1, larger than the size of the core polypeptide (95 kDa)
G C Frech et al.
Nature, 340(6235), 642-645 (1989-08-24)
Voltage-activated potassium channels play an important part in the control of excitability in nerve and muscle. Different K+ channels are involved in establishing the resting potential, determining the duration of action potentials, modulation of transmitter release, and in rhythmic firing
P M Hwang et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 13(4), 1569-1576 (1993-04-01)
We have localized CDRK and DRK1, two novel K+ channels of the Shab subfamily by immunohistochemistry. The two channels are closely related in structure with about 90% amino acid identity in the N-terminal and middle portions and 60% identity in
Marjaana A Peltola et al.
EMBO reports, 12(12), 1293-1299 (2011-11-08)
Kv2.1 is a potassium channel α-subunit abundantly expressed throughout the brain. It is a main component of delayed rectifier current (I(K)) in several neuronal types and a regulator of excitability during high-frequency firing. Here we identify AMIGO (amphoterin-induced gene and
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