R4653
モノクロナール抗hnRNP-A2/B1 マウス宿主抗体
clone DP3B3, purified from hybridoma cell culture
別名:
抗不均一核リボ核タンパク質A2/B1抗体
ログインで組織・契約価格をご覧ください。
サイズを選択してください
この商品について
Conjugate:
unconjugated
Clone:
DP3B3, monoclonal
Application:
ARR, ICC, IP, WB
Species reactivity:
rat, human, bovine, hamster, monkey, chicken, mouse, canine
Citations:
24
Technique(s):
immunocytochemistry: suitable, immunoprecipitation (IP): suitable, microarray: suitable, western blot: 1-2 μg/mL using total cell extract from 293T cell line
Uniprot accession no.:
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
DP3B3, monoclonal
form
buffered aqueous solution
mol wt
antigen ~36 kDa
species reactivity
rat, human, bovine, hamster, monkey, chicken, mouse, canine
technique(s)
immunocytochemistry: suitable, immunoprecipitation (IP): suitable, microarray: suitable, western blot: 1-2 μg/mL using total cell extract from 293T cell line
isotype
IgG2a
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... HNRNPA2B1(3181)
mouse ... Hnrnpa2b1(53379)
rat ... Hnrnpa2b1(362361)
Immunogen
組み換えヒトhnRNP-A2。
Physical form
0.01M PBS溶液(pH 7.4, 15mMアジ化ナトリウム含有)。
Application
Monoclonal Anti-hnRNP-A2/B1 antibody produced in mouse been used in :
- enzyme linked immunosorbent assay (ELISA)
- immunoblotting
- immunoprecipitation
- immunocytochemistry
Biochem/physiol Actions
In cells, it actively participates in pre-messenger RNA (pre-mRNA) processing, mRNA metabolism and transportation. It is overexpressed in the initial stage of lung cancer and in premalignant lesions. It also participates in neurodegeneration mediated by rCGG (repeats).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Monoclonal Anti-hnRNP-A2/B1 (mouse IgG2a isotype) is derived from the DP3B3 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with recombinant human hnRNP-A2. hnRNP-A2/B1 proteins are located in the nucleus of most tissues cells. However, the hnRNP-A2 protein is found also in the cytoplasm of skin and esophagus cells. In rat brain, hnRNP-A2/B1 proteins are found in neurons in the cerebral cortices, hippocampal formation, olfactory regions, caudate-putamin and the supraoptic nucleus of the hypothalamus.
適切な製品が見つかりませんか。
製品選択ツール.をお試しください
保管分類
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
R4653-200UL: + R4653-VAR: + R4653-BULK:
jan
PLEKHA7 defines an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications
Kourtidis A and Anastasiadis PZ
Cell Cycle, 15(4), 498-505 (2016)
Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB
Aksenova V, et al.
Oncotarget, 4(2), 362-372 (2013)
Amanda M Nelson et al.
The Journal of investigative dermatology, 126(10), 2178-2189 (2006-04-01)
Isotretinoin (13-cis retinoic acid (13-cis RA)) is the most potent inhibitor of sebum production, a key component in the pathophysiology of acne, yet its mechanism of action remains largely unknown. The effects of 13-cis RA, 9-cis retinoic acid (9-cis RA)
RNA-binding proteins hnRNP A2/B1 and CUGBP1 suppress fragile X CGG premutation repeat-induced neurodegeneration in a Drosophila model of FXTAS
Sofola OA, et al.
Neuron, 55(4), 565-571 (2007)
Immunohistochemical study of the hnRNP A2 and B1 in the rat forebrain
Mizukami K, et al.
Neuroreport, 11(14), 3099-3102 (2000)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）