RAB0274
Mouse IL-1 β ELISA Kit
for serum, plasma and cell culture supernatant
別名:
Il-1 beta, Interleukin-1 beta
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この商品について
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
mouse ... Il1b(16176)
Input:
sample type plasma
sample type serum
sample type cell culture supernatant(s)
sample type serum
sample type cell culture supernatant(s)
Species reactivity:
mouse
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type plasma
sample type serum
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 2.74-2000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Il1b(16176)
Application
Mouse IL-1 β ELISA Kit has been used to determine the presence of interleukin-1β (IL-1β) in plasma sample. It has also been used to determine the serum concentration levels of IL-1β.
General description
The Mouse IL-1β ELISA (enzyme-linked immunosorbent assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse IL-1β in serum, plasma, cell culture supernatants and urine. Interleukin-1β (IL-1β) cytokine is generated by monocytes, dendritic cells, macrophages and keratinocytes. Pro-IL-1β, an IL-1β precursor undergoes proteolytic cleavage to produce its active form of 17 kDa. IL-1β is a potent inflammatory cytokine, and mediates inflammation through proinflammatory molecules: cyclooxygenase-2 (COX2) and nitric oxide. IL-1β release is stimulated by injury and increased levels are observed in response to severe pain. It has its main function in T-cell activation, antigen recognition and T-helper cell 17 cell development. IL-1β is also responsible for the formation of IL-17 and IL-22 by nature killer T (NKT) cells and NK cells. It is known to induce inflammation in psoriasis and rheumatoid arthritis. IL-1β controls intercellular adhesion molecule-1 expression. It is significantly associated with bone damage and vascular injury.
Immunogen
Recombinant Mouse IL-1 β
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
保管分類
10 - Combustible liquids
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Please refer to KIT Component information
pdsc
Please refer to KIT Component information
prtr
Please refer to KIT Component information
fsl
Please refer to KIT Component information
ishl_indicated
Please refer to KIT Component information
ishl_notified
Please refer to KIT Component information
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キットコンポーネントの情報を参照してください
jan
Identification of interleukin-1 beta as a key mediator in the upregulation of Cav3. 2--USP5 interactions in the pain pathway
Stemkowski PL, et al.
Molecular Pain, 13(36) (2017)
Effect of HI-6 on cytokines production after immunity stimulation by keyhole limpet hemocyanin in a mouse model
Pohanka M
Neuro Endocrinology Letters, 35(4), 101-103 (2014)
Protective effect and mechanism of ginsenoside Rg1 in cerebral ischaemia-reperfusion injury in mice
Wang L, et al
Biomedicine and Pharmacotherapy, 99(4), 876-882 (2018)
CCN1 promotes IL-1beta production in keratinocytes by activating p38 MAPK signaling in psoriasis
Sun Y, et al.
Scientific reports, 7, 43310-43310 (2017)
Interleukin-1beta induces intercellular adhesion molecule-1 expression, thus enhancing the adhesion between mesenchymal stem cells and endothelial progenitor cells via the p38 MAPK signaling pathway
Guo J, et al.
International Journal of Molecular Medicine, 41(4), 1976-1982 (2018)
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