S1827
デオキシコール酸ナトリウム
別名:
3α,12α-ジヒドロキシ-5β-コラン酸 ナトリウム塩, 7-デオキシコール酸 ナトリウム塩, デスオキシコール酸 ナトリウム塩
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この商品について
実験式（ヒル表記法）:
C24H39NaO4
CAS番号:
分子量:
414.55
EC Number:
206-132-7
UNSPSC Code:
12161900
NACRES:
NA.21
Beilstein/REAXYS Number:
3581950
MDL number:
InChI key
FHHPUSMSKHSNKW-SMOYURAASA-M
InChI
1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
SMILES string
[Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
biological source
animal
assay
≥98% (HPLC)
form
powder
mol wt
micellar avg mol wt 1200-5000
aggregation number
3-12
CMC
2-6 mM (20-25°C)
HLB
16
suitability
suitable for manufacturing use
Quality Level
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General description
Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.
M-Clarity Program
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
M-Clarity Program
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
Legal Information
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
保管分類
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Dov B Ballak et al.
Nature communications, 5, 4711-4711 (2014-09-04)
Cytokines of the IL-1 family are important modulators of obesity-induced inflammation and the development of systemic insulin resistance. Here we show that IL-1 family member IL-37, recently characterized as an anti-inflammatory cytokine, ameliorates obesity-induced inflammation and insulin resistance. Mice transgenic
Jamie A Greig et al.
PLoS pathogens, 11(1), e1004630-e1004630 (2015-01-27)
The opportunistic human fungal pathogen, Candida albicans, undergoes morphological and transcriptional adaptation in the switch from commensalism to pathogenicity. Although previous gene-knockout studies have identified many factors involved in this transformation, it remains unclear how these factors are regulated to
Jelke J Fros et al.
The Journal of general virology, 96(Pt 3), 580-589 (2014-11-15)
The unfolded protein response (UPR) is a cellular defence mechanism against high concentrations of misfolded protein in the endoplasmic reticulum (ER). In the presence of misfolded proteins, ER-transmembrane proteins PERK and IRE1α become activated. PERK phosphorylates eIF2α leading to a
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