S4701
トシル酸スプラタスト
≥98% (HPLC)
別名:
(+/-)-[2-[4-(3-エトキシ-2-ヒドロキシプロポキシ)フェニルカルバモイル]-エチル] ジメチルスルホニウムp-トルエンスルホナート, IPD-1151T, ST
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この商品について
実験式（ヒル表記法）:
C16H26SNO4 · C7H7SO3
CAS番号:
分子量:
499.64
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C16H25NO4S.C7H8O3S/c1-4-20-11-14(18)12-21-15-7-5-13(6-8-15)17-16(19)9-10-22(2)3;1-6-2-4-7(5-3-6)11(8,9)10/h5-8,14,18H,4,9-12H2,1-3H3;2-5H,1H3,(H,8,9,10)
SMILES string
Cc1ccc(cc1)S([O-])(=O)=O.CCOCC(O)COc2ccc(NC(=O)CC[S+](C)C)cc2
InChI key
RYVJQEZJUFRANT-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: >20 mg/mL
storage temp.
room temp
Quality Level
Application
Suplatast tosylate may be used in immune-signaling studies.
Biochem/physiol Actions
スプラタストトシル酸塩は、抗アレルギー・サイトカイン産生調節剤です。
Suplatast tosylate is a dimethylsulfonium compound downregulates the expression of histamine H1 receptor gene, suppresses the activity of histidine decarboxylase and regulates IL-4 mRNA. It inhibits the release of histamines and regulates the production of IgE.1,2 Suplatast tosylate is effective in the treatment of mild-to-moderate persistent asthma in children.3
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
S4701-BULK: + S4701-10MG: + S4701-VAR: + S4701-50MG:
jan
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Sensors (Basel, Switzerland), 19(14) (2019-07-25)
Internet of Things (IoT) devices have become increasingly widespread. Despite their potential of improving multiple application domains, these devices have poor security, which can be explored by attackers to build large-scale botnets. In this work, we propose a host-based approach
Robert J Mallis et al.
Journal of biomolecular NMR, 73(6-7), 319-332 (2019-03-01)
Early studies of T cell structural biology using X-ray crystallography, surface plasmon resonance (SPR) and isothermal titration calorimetry (ITC) focused on a picture of the αβT cell receptor (αβTCR) component domains and their cognate ligands (peptides bound to MHC molecules
Juqing Zhang et al.
Applied biochemistry and biotechnology, 189(1), 26-36 (2019-03-13)
Since the birth of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9, the new genome engineering technology has become a hot topic in the scientific community. However, for swine, the system of pig cells' homology directed repair (HDR) is generally unstable
Tien-Chi Hou et al.
OncoTargets and therapy, 12, 6439-6451 (2019-09-10)
This study integrated clinical outcomes and radiomics of advanced thoracic esophageal squamous cell carcinoma patients receiving neoadjuvant concurrent chemoradiotherapy (NACCRT) to establish a novel constraint model for predicting radiation pneumonitis (RP). We conducted a retrospective review for thoracic advanced esophageal
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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