SAB1305554
Anti-β-Actin (ACTB) Antibody
mouse monoclonal, 137CT26.1.1
別名:
ACTB, Actin, cytoplasmic 1, Actin, cytoplasmic 1, N-terminally processed, Beta-actin
ログインで組織・契約価格をご覧ください。
サイズを選択してください
この商品について
UNSPSC Code:
12352203
NACRES:
NA.41
Clone:
137CT26.1.1, monoclonal
Species reactivity:
mouse, human
Application:
IF, IHC, WB
Technique(s):
immunofluorescence: 1:10-1:50, immunohistochemistry: 1:25, western blot: 1:1000
Citations:
5
Uniprot accession no.:
製品名
MONOCLONAL ANTI-BETA-ACTIN antibody produced in mouse, clone 137CT26.1.1, IgG fraction of antiserum, buffered aqueous solution
biological source
mouse
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
137CT26.1.1, monoclonal
form
buffered aqueous solution
mol wt
41737 Da
species reactivity
mouse, human
technique(s)
immunofluorescence: 1:10-1:50, immunohistochemistry: 1:25, western blot: 1:1000
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ACTB(60)
Application
Monoclonal Anti-Beta-Actin antibody produced in mouse has been used in western blotting at a dilution of 1:1000.
Biochem/physiol Actions
β-actin (ACTB) forms the core of the cell cytoskeleton. The polymerization of β-actin is essential for cell physiology. It may serve as a potential chemotherapeutic agent. Mutation in the ACTB gene is implicated in sensory hearing loss, delayed-onset generalized dystonia and a combination of ventral midline malformations. A loss-of-function mutation in the ACTB gene may cause intellectual disability.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
β-actin (ACTB), a member of the actin multigene family, is an isoform of actin-associated with non-muscle cells. ACTB is a housekeeping gene mapped to human chromosome 7p22.1.
Physical form
Supplied in PBS with 0.09% (W/V) sodium azide
適切な製品が見つかりませんか。
製品選択ツール.をお試しください
保管分類
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Sequence and structural analysis of beta-actin protein of fishes, using bioinformatics tools and techniques
Acharya UR, et al.
International journal of biosciences, 4(11) (2014)
Sara Cuvertino et al.
American journal of human genetics, 101(6), 1021-1033 (2017-12-09)
ACTB encodes β-actin, an abundant cytoskeletal housekeeping protein. In humans, postulated gain-of-function missense mutations cause Baraitser-Winter syndrome (BRWS), characterized by intellectual disability, cortical malformations, coloboma, sensorineural deafness, and typical facial features. To date, the consequences of loss-of-function ACTB mutations have
Induction of drug resistance in human hepatoma cells cultured on a silicate fiber based 3d scaffold
Mizutami T, et al.
Advances in Biochemical Engineering null
Zunshu Du et al.
Aging cell, 20(8), e13437-e13437 (2021-07-23)
Synapse degeneration correlates strongly with cognitive impairments in Alzheimer's disease (AD) patients. Soluble Amyloid-beta (Aβ) oligomers are thought as the major trigger of synaptic malfunctions. Our earlier studies have demonstrated that Aβ oligomers interfere with synaptic function through N-methyl-D-aspartate receptors
Qifeng Deng et al.
Redox biology, 49, 102217-102217 (2021-12-24)
Maintaining host iron homeostasis is an essential component of nutritional immunity responsible for sequestrating iron from pathogens and controlling infection. Nucleotide-oligomerization domain-like receptors (NLRs) contribute to cytoplasmic sensing and antimicrobial response orchestration. However, it remains unknown whether and how NLRs
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）