SAB4301399
Anti-phospho-DRP1 (pSer637) antibody produced in rabbit
affinity isolated antibody
別名:
DLP1, DNM1L, DRP1, DVLP, Dymple
ログインで組織・契約価格をご覧ください。
サイズを選択してください
この商品について
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human
Application:
WB
Citations:
10
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
82 kDa
species reactivity
human
concentration
1.0 mg/mL
technique(s)
western blot: 1:500-1:1000 (Cell Lysate)
isotype
IgG
accession no.
NP_036192.2.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pSer637)
Quality Level
Gene Information
human ... DNM1L(10059)
General description
Dynamin related protein 1 (DRP1) is a dynamin-related guanosine triphosphatase. The gene is located on human chromosome 12p11.21. DRP1 is a cytosolic protein, which is also present on the outer mitochondrial membrane.
Immunogen
Peptide sequence around phosphorylation site of Serine637(K-L-S(p)-A-R) derived from Human DRP1.
Application
Anti-phospho-DRP1 (pSer637) antibody produced in rabbit has been used in immunoblotting and western blotting.
Biochem/physiol Actions
Dynamin related protein 1 (DRP1) is an important regulator of mitochondrial fission and peroxisomal division. It regulates proper mitochondrial function, apoptosis and necrosis. Mutations in this gene is associated with Alzheimer′s disease.
The antibody detects endogenous levels of DRP1 only when phosphorylated at serine 637.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
適切な製品が見つかりませんか。
製品選択ツール.をお試しください
保管分類
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
SAB4301399-100UL:
jan
Legionella pneumophila modulates mitochondrial dynamics to trigger metabolic repurposing of infected macrophages
Escoll P, et al.
Cell host & microbe, 22(3), 302-316 (2017)
UBIAD1 protects against oxygen-glucose deprivation/reperfusion-induced multiple subcellular organelles injury through PI3K/AKT pathway in N2A cells
Huang Y and Hu Z
Journal of Cellular Physiology, 233(9), 7480-7496 (2018)
S-nitrosylation of Drp1 mediates ?-amyloid-related mitochondrial fission and neuronal injury
Cho DH, et al.
Science, 324(5923), 102-105 (2009)
Receptor-mediated Drp1 oligomerization on endoplasmic reticulum
Ji WK, et al.
The Journal of Cell Biology, 216(12), 4123-4139 (2017)
Downregulation of Drp1, a fission regulator, is associated with human lung and colon cancers
Kim YY, et al.
Acta biochimica et biophysica Sinica, 50(2), 209-215 (2018)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）