SAB4500631
Anti-CHOP, N-Terminal antibody produced in rabbit
affinity isolated antibody
別名:
C/EBP-homologous protein, DDIT3, DNA-damage inducible transcript 3, GADD153, Growth arrest and DNA-damage-inducible protein GADD153
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この商品について
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, IHC, WB
Citations:
7
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 19 kDa
species reactivity
human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000, immunofluorescence: 1:100-1:500, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... DDIT3(1649)
General description
Anti-CHOP Antibody detects endogenous levels of total CHOP protein.
CCAAT/enhancer-binding protein homologous protein (CHOP) is a transcriptional regulator, that is located on human chromosome 12q13. It is also known as DNA damage inducible transcript 3 (DDIT3).
Immunogen
The antiserum was produced against synthesized peptide derived from human CHOP.
Immunogen Range: 15-64
Immunogen Range: 15-64
Application
Anti-CHOP, N-Terminal antibody has been used in protein extraction and western blotting.
Biochem/physiol Actions
CCAAT/enhancer-binding protein homologous protein (CHOP) controls endoplasmic reticulum (ER) stress-mediated apoptosis. It also modulates the transcription of cellular lipid metabolism. CHOP controls chronic kidney disease–induced vascular calcification.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
SAB4500631-100UG:
jan
Sujata Saraswat Ohri et al.
Journal of neurotrauma, 29(3), 579-588 (2011-09-22)
Manipulation of various components of the endoplasmic reticulum (ER) stress response (ERSR) has led to functional recovery in diabetes, cancer, and several neurodegenerative diseases, indicating its use as a potential therapeutic intervention. One of the downstream pro-apoptotic transcription factors activated
Protective role of magnesium isoglycyrrhizinate in non-alcoholic fatty liver disease and the associated molecular mechanisms
Xu Q, et al.
International Journal of Molecular Medicine, 38(1), 275-282 (2016)
C/EBP homologous protein modulates liraglutide-mediated attenuation of non-alcoholic steatohepatitis
Rahman K, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 96(8), 895-908 (2016)