T0699
トリクロロ酢酸 溶液
6.1 N
別名:
TCA
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この商品について
化学式:
Cl3CCOOH
CAS番号:
分子量:
163.39
UNSPSC Code:
12352106
NACRES:
NA.26
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
970119
General description
トリクロロ酢酸（TCA）は強酸です。飲料水のpHで、TCAはほぼ塩として存在します。
Application
トリクロロ酢酸溶液は、以下の用途に使用されています：
- N-ホルミルキヌレニンを加水分解しキヌレニンを生成するインドールアミン2,3-ジオキシゲナーゼ（IDO）酵素アッセイ
- ヒト肺動脈平滑筋細胞（HPASMC）の増殖
- 粉砕組織の処理およびタンパク質抽出・定量時のタンパク質の沈降
Biochem/physiol Actions
タンパク質の沈殿にはトリクロロ酢酸溶液が古くから用いられています。定量沈降別のタンパク質濃度の測定に用いることができます。トリクロロ酢酸は、顕微鏡下で脱灰剤および固定剤としても使用できる。
全身毒性が確認されていないトリクロロ酢酸（TCA）は、古くからの表面ピーリング剤として使用されています。ペルオキシソーム増殖因子です。
signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3
target_organs
Respiratory system
保管分類
8A - Combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Guillaume Laflamme et al.
Cell reports, 26(11), 2875-2889 (2019-03-14)
The segregation of chromosomes is a critical step during cell division. This process is driven by the elongation of spindle microtubules and is tightly regulated by checkpoint mechanisms. It is unknown whether microtubules affect checkpoint responses as passive contributors or
Alan Mortensen et al.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 18(1), 55-62 (2012-10-17)
The ratio of the nitric oxide synthase (NOS) cofactor tetrahydrobiopterin (BH(4)) to its oxidized form dihydrobiopterin (BH(2)) has been suggested as an index of endothelial dysfunction. Consequently, much effort has been put into preserving the in vivo equilibrium between these
Ying Wang et al.
Diabetes, 63(8), 2643-2655 (2014-03-13)
After diabetes, the heart has a singular reliance on fatty acid (FA) for energy production, which is achieved by increased coronary lipoprotein lipase (LPL) that breaks down circulating triglycerides. Coronary LPL originates from cardiomyocytes, and to translocate to the vascular
Verena Pfahler et al.
The New phytologist, 197(1), 186-193 (2012-10-31)
The objective of this study was to investigate the isotopic composition of oxygen bound to phosphate (δ(18)O-PO(4)) in different phosphorus (P) pools in plant leaves. As a model plant we used soybean (Glycine max cv Toliman) grown in the presence
Inga Müller et al.
PloS one, 9(5), e97285-e97285 (2014-05-27)
Members of the MYC family are the most frequently deregulated oncogenes in human cancer and are often correlated with aggressive disease and/or poorly differentiated tumors. Since patients with MYCN-amplified neuroblastoma have a poor prognosis, targeting MYCN using small molecule inhibitors
プロトコル
This procedure may be used for the determination of Amyloglucosidase activity using starch as the substrate.
This procedure may be used for all Ficin products.
To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.
This procedure may be used for determination of Pepsin activity using hemoglobin as the substrate. It is a spectrophotometric stop rate determination.
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