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Merck

T4071

L-トレオニン

別名:

(2S,3R)-2-アミノ-3-ヒドロキシ酪酸

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この商品について

化学式:
CH3CH(OH)CH(NH2)CO2H
CAS番号:
分子量:
119.12
EC Number:
200-774-1
UNSPSC Code:
12352209
NACRES:
NA.26
Beilstein/REAXYS Number:
1721646
MDL number:
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InChI

1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1

InChI key

AYFVYJQAPQTCCC-GBXIJSLDSA-N

SMILES string

C[C@@H](O)[C@H](N)C(O)=O

biological source

non-animal source

assay

≥98.5%

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, heavy metals, trace metals, residual solvents, tested

mp

256 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL

suitability

suitable for manufacturing use

foreign activity

cytotoxicity, tested

Quality Level

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Application

L-Threonine is a β-hydroxy-α-amino acid. It is an essential amino acid and can be used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Tamara Seredenina et al.
Antioxidants & redox signaling, 23(5), 490-513 (2014-02-04)
Voltage-gated proton channels are increasingly implicated in cellular proton homeostasis. Proton currents were originally identified in snail neurons less than 40 years ago, and subsequently shown to play an important auxiliary role in the functioning of reactive oxygen species (ROS)-generating
Chang-Ching Liu et al.
Molecular and cellular biology, 34(1), 57-70 (2013-10-30)
In budding yeast (Saccharomyces cerevisiae), the cell cycle-dependent telomere elongation by telomerase is controlled by the cyclin-dependent kinase 1 (Cdk1). The telomere length homeostasis is balanced between telomerase-unextendable and telomerase-extendable states that both require Cdc13. The recruitment of telomerase complex
Mario Ost et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(4), 1314-1328 (2014-12-11)
Recent studies on mouse and human skeletal muscle (SM) demonstrated the important link between mitochondrial function and the cellular metabolic adaptation. To identify key compensatory molecular mechanisms in response to chronic mitochondrial distress, we analyzed mice with ectopic SM respiratory
Sarah Schmidt et al.
Journal of leukocyte biology, 98(1), 5-14 (2015-02-04)
The deoxynucleoside triphosphate triphosphohydrolase and 3' → 5' exonuclease SAMHD1 restricts HIV-1 infection in noncycling hematopoietic cells in vitro, and SAMHD1 mutations are associated with AGS. Little is known about the in vivo expression and functional regulation of this cellular
Anne-Sophie Van Rompuy et al.
Journal of neuropathology and experimental neurology, 73(2), 159-174 (2014-01-16)
Mutations in the parkin gene are the most common cause of early-onset autosomal recessive Parkinson disease (PD). The pathogenic mechanisms of how parkin mutations lead to the development of PD are not fully understood. Studies of cell cultures and of

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