Z0153
ZM 241385
≥98% (HPLC), adenosine A2A antagonist, powder
別名:
4-(-2-[7-アミノ-2-{2-フリル}{1,2,4}トリアゾロ{2,3-a} {1,3,5}トリアジン-5-イル-アミノ]エチル)フェノール
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この商品について
実験式（ヒル表記法）:
C16H15N7O2
CAS番号:
分子量:
337.34
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
製品名
ZM 241385, ≥98% (HPLC)
SMILES string
Nc1nc(NCCc2ccc(O)cc2)nc3nc(nn13)-c4ccco4
InChI key
PWTBZOIUWZOPFT-UHFFFAOYSA-N
InChI
1S/C16H15N7O2/c17-14-20-15(18-8-7-10-3-5-11(24)6-4-10)21-16-19-13(22-23(14)16)12-2-1-9-25-12/h1-6,9,24H,7-8H2,(H3,17,18,19,20,21,22)
assay
≥98% (HPLC)
form
powder
color
white to tan
solubility
DMSO: >15 mg/mL
storage temp.
room temp
Quality Level
Features and Benefits
この化合物はHandbook of Receptor Classification and Signal TransductionのAdenosine Receptorsのページに取り上げられています。ハンドブックの他のページを閲覧するには、ここをクリックしてください。
Biochem/physiol Actions
ZM 241385は、強力かつ選択的なアデノシンA2A拮抗薬です。
ZM 241385は、強力かつ選択的なアデノシンA2A拮抗薬です。A2A受容体は、心筋酸素消費量と冠血流量の調節に関与しており、脳内で高度に発現され、グルタミン酸とドーパミンの放出の調節において重要な役割を果たしています。ZM 241385は神経保護作用があり、パーキンソン病や他の神経変性疾患での使用について研究が進められています。
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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