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この商品について
実験式（ヒル表記法）:
C4H6N4O3S2
CAS番号:
分子量:
222.25
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
製品名
アセタゾールアミド, United States Pharmacopeia (USP) Reference Standard
InChI
1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)
SMILES string
CC(=O)Nc1nnc(s1)S(N)(=O)=O
InChI key
BZKPWHYZMXOIDC-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
acetazolamide
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
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関連するカテゴリー
Application
炭酸脱水酵素インヒビタ-です。脳血流を増加させます。
Acetazolamide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Acetazolamide Compounded Oral Suspension
- Acetazolamide Extended-Release Capsules
- Acetazolamide for Injection
- Acetazolamide Tablets
Biochem/physiol Actions
水チャネルとの相互作用により膜の水透過性を阻害します。
General description
この製品は薬局方標準品です。発行元の薬局方により製造・供給されています。MSDSを含む製品情報などの詳しい情報は、発行元の薬局方のウェブサイトよりご確認ください。
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Gladys E Granero et al.
Expert opinion on drug delivery, 7(8), 943-953 (2010-06-23)
Acetazolamide (ACZ), a carbonic anhydrase inhibitor (CAI), and other oral CAIs have been an integral part of antiglaucoma therapy for > 40 years. ACZ is used orally for the reduction of intraocular pressure in patients suffering from glaucoma. However, this
David E Leaf et al.
Journal of applied physiology (Bethesda, Md. : 1985), 102(4), 1313-1322 (2006-10-07)
Acetazolamide, a potent carbonic anhydrase (CA) inhibitor, is the most commonly used and best-studied agent for the amelioration of acute mountain sickness (AMS). The actual mechanisms by which acetazolamide reduces symptoms of AMS, however, remain unclear. Traditionally, acetazolamide's efficacy has
Indu Pal Kaur et al.
International journal of pharmaceutics, 248(1-2), 1-14 (2002-11-14)
Through this review it is contemplated that acetazolamide (ACZ), an age-old treatment for glaucoma with a myriad of side effects and inadequate topical effectiveness, may be formulated into a topically effective agent by utilizing various newer formulation approaches of ocular
G Settakis et al.
European journal of neurology, 10(6), 609-620 (2003-12-04)
Pathologic processes affecting the brain vessels may damage cerebral vasodilatory capacity. Early detection of cerebral dysfunction plays an important role in the prevention of cerebrovascular diseases. In recent decades acetazolamide (AZ) has frequently been used for this purpose. In the
Neil D Ritchie et al.
Journal of travel medicine, 19(5), 298-307 (2012-09-05)
Acetazolamide has been reported to be effective in the prevention of acute mountain sickness (AMS). Our aim was to conduct a systematic review of randomized, placebo-controlled trials of acetazolamide in the prevention of AMS. Studies were identified by searching the
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