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この商品について
実験式（ヒル表記法）:
C17H17NCl2 · HCl
CAS番号:
分子量:
342.69
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI
1S/C17H17Cl2N.ClH/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11;/h2-6,8,10,12,17,20H,7,9H2,1H3;1H/t12-,17-;/m0./s1
SMILES string
ClC1=C(Cl)C=CC([C@H]2C3=C(C=CC=C3)[C@@H](NC)CC2)=C1.[H]Cl
InChI key
BLFQGGGGFNSJKA-XHXSRVRCSA-N
grade
pharmaceutical primary standard
API family
sertraline
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
Gene Information
human ... SLC6A4(6532)
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General description
Sertraline hydrochloride is a SSRI i.e selective serotonin reuptake inhibitor. It is mainly used in treating psychiatric disorders. It also is effective in treating hypotension occurring in disorders like neurocardiogenic syncope and idiopathic orthostatic hypotension which is affected by autonomic dysfunction.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Sertraline hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Sertraline Hydrochloride Oral Solution
- Sertraline Hydrochloride Tablets
Biochem/physiol Actions
セロトニン再取り込みの選択的インヒビタ-であり、抗うつ薬です。
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
保管分類
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
1612539-100MG:
jan
Aquatic ecotoxicity of the selective serotonin reuptake inhibitor sertraline hydrochloride in a battery of freshwater test species.
Minagh E
Ecotox. Environ. Safety, 72(2), 434-440 (2009)
Effect of sertraline hydrochloride on dialysis hypotension.
Dheenan S
American Journal of Kidney Diseases, 31(4), 624-630 (1998)
Marilyn X Zhou et al.
Journal of chromatography. A, 1052(1-2), 13-23 (2004-11-06)
Sertraline is a basic compound and of pharmaceutical application for antidepressant treatment. The compound has two chiral centers. Separation of the three enantiomeric impurities from the parent compound is challenging. In this study, we successfully separated all four stereoisomers by
Goudarz Akasheh et al.
Urology, 83(4), 800-804 (2014-02-18)
To investigate the effects of sertraline on semen parameters and comparison of its effect with behavioral therapy (BT) in men with primary premature ejaculation. In this single-blinded clinical trial, a total of 60 married men with primary premature ejaculation were
Depression in a Pakistani woman.
Anita Aijaz et al.
The American journal of psychiatry, 171(7), 729-731 (2014-07-02)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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