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74104

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride

Name: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride
Brand: ALDRICH

≥97.0% (calc. on dry substance, AT), for peptide synthesis

Synonym(s):

DMTMM, MMTM

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₇ClN₄O₃

CAS Number:

3945-69-5

Molecular Weight:

276.72

NACRES:

NA.22

PubChem Substance ID:

57652501

UNSPSC Code:

12352005

MDL number:

MFCD03613550

Beilstein/REAXYS Number:

8026872

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Properties

Product Name

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride, 95% (HPLC)

Quality Level

100

assay

95% (HPLC)

form

powder

reaction suitability

reaction type: Coupling Reactions

impurities

≤17 wt. % water

application(s)

peptide synthesis

functional group

ether

storage temp.

−20°C

SMILES string

[Cl-].COc1nc(OC)nc(n1)[N+]2(C)CCOCC2

InChI

1S/C10H17N4O3.ClH/c1-14(4-6-17-7-5-14)8-11-9(15-2)13-10(12-8)16-3;/h4-7H2,1-3H3;1H/q+1;/p-1

InChI key

BMTZEAOGFDXDAD-UHFFFAOYSA-M

Description

Application

Reagent for activating carboxylic acids in solution and solid phase peptide synthesis; superior or comparable to the most popular coupling reagents

4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride can be used as a condensing agent for the following transformations:

Condensation of carboxylic acids and amines to the corresponding amides in tetrahydrofuran.
Esterification of carboxylic acids with alcohols to the corresponding esters.
Conversion of carboxylic acids to the corresponding Weinreb amides in protic solvents.