428020
Latrunculin B
from Latrunculia magnifica, ≥95% (HPLC), solid, actin polymerization inhibitor, Calbiochem®
Synonym(s):
Latrunculin B, Latrunculia magnifica
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About This Item
Product Name
Latrunculin B, Latrunculia magnifica, Latrunculin B, CAS 76343-94-7, is a unique marine toxin that inhibits actin polymerization and disrupts microfilament organization. It is 10 to 100-fold more potent than cytochalasins.
Quality Level
description
Merck USA index - 14, 5378
assay
≥95% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
off-white to yellow
solubility
DMSO: 25 mg/mL, ethanol: 25 mg/mL, methanol: 50 mg/mL
shipped in
ambient
storage temp.
−20°C
SMILES string
S1C[C@H](NC1=O)[C@@]2(O[C@H]3C[C@@H](OC(=O)\C=C(/CC\C=C/[C@H](CC3)C)\C)C2)O
InChI
1S/C20H29NO5S/c1-13-5-3-4-6-14(2)9-18(22)25-16-10-15(8-7-13)26-20(24,11-16)17-12-27-19(23)21-17/h3,5,9,13,15-17,24H,4,6-8,10-12H2,1-2H3,(H,21,23)/b5-3-,14-9-/t13-,15-,16-,17+,20-/m1/s1
InChI key
NSHPHXHGRHSMIK-JRIKCGFMSA-N
General description
Biochem/physiol Actions
Actin polymerization
Other Notes
de Oliveira, C.A., and Mantovani, B. 1988. Life Sci.43, 1825.
Coue, M., et al. 1987. FEBS Lett.213, 316.
Spector, I., et al. 1983. Science219, 493.
Legal Information
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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