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Merck

8.55050

Sigma-Aldrich

Dansyl NovaTag® resin

Novabiochem®

Synonym(s):

N-Dansyl-NÆ-Fmoc-ethylenediamine MPB-AM resin

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About This Item

UNSPSC Code:
12352116
NACRES:
NA.22

Key Documents

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Quality Level

200

product line

NovaSyn® TG
Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

15-25°C

Related Categories

General description

Dansyl NovaTag resin is an ideal tool for the synthesis of Dansyl-labeled peptides. The resin pre-loaded with the Dansyl chromophore can be used directly in Fmoc SPPS. Following peptide assembly under standard Fmoc SPPS conditions, cleavage with TFA affords the Dansyl-labeled peptide. This resin has been recently used to dansyl-labeled amyloid-RGD peptides [1] and FRET probes for mercury binding protein MerP [2].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Literature references

[1] S. L. Gras, et al. (2008) Biomaterials, 29, 1553.
[2] B. R. White, et al. (2008) Analyst,, 133, 65

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.30 - 0.60 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly styrene - 1 & DVB 100 - 200 mesh

Other Notes

Replaces: 04-12-3900

Legal Information

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
NOVATAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Articles

Peptide-Labeling

The spectral properties of Novabiochem®’s chromogenic and fluorogenic derivatives are invaluable tools for biochemistry, having numerous applications in enzymology, protein chemistry, immunology and histochemistry. Novabiochem® range offers one of the most extensive ranges of labeling reagents for the synthesis of such peptides, including the unique NovaTag™ resins for the production of C-terminally-labeled peptide

Global Trade Item Number

SKUGTIN
8.55050.810004027269111458