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Merck

A5131

L-Arginine monohydrochloride

≥98% (HPLC)

Synonym(s):

(S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride, (S)-(+)-Arginine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C6H14N4O2 · HCl
CAS Number:
1119-34-2
Molecular Weight:
210.66
NACRES:
NA.26
PubChem Substance ID:
24890944
UNSPSC Code:
12352209
EC Number:
214-275-1
MDL number:
MFCD00064550
Beilstein/REAXYS Number:
3631658

Key Documents

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Product Name

L-Arginine monohydrochloride, reagent grade, ≥98% (HPLC), powder

grade

reagent grade

assay

≥98% (HPLC)

form

powder

color

white

mp

>235 °C

solubility

H2O: 50 mg/mL

application(s)

cell analysis

Quality Level

200

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Application

L-Arginine monohydrochloride has been used to study the effects of amino acids in promoting food consumption in Drosophila melanogaster. It has also been used to develop a non-invasive chronic pancreatitis model of rat.

Biochem/physiol Actions

L-Arginine is a semi-essential amino acid. This dibasic amino acid acts as a precursor for creatinine and is a natural constituent of most of the dietary proteins.
Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Severe Chronic Pancreatitis due to Recurrent Acute Injury: Non-Invasive Chronic Pancreatitis Model of Rat
Surendra Sharma
Pancreas (2016)
Yang Liu et al.
Biochemical and biophysical research communications, 525(3), 620-625 (2020-03-03)
The circadian clock, a biochemical oscillator, plays a fundamental role in health and diseases. Ferroptosis, a type of regulated cell death driven by oxidative stress, is a prominent feature in iron-induced tissue injury. However, whether an impaired circadian clock contributes
J. P. Felix D'Mello
Amino Acids in Human Nutrition and Health (2012)
An internal sensor detects dietary amino acids and promotes food consumption in Drosophila
Zhe Yang
Nature (2017)
Yangyang Hu et al.
Journal of cellular physiology, 234(12), 21988-21998 (2019-05-07)
The severity of acute pancreatitis (AP) is greatly attributed to the pancreatic acinar cell (PAC) death response. It has been established that the apoptosis-inducing therapy can protect against experimental pancreatitis and have great clinical therapeutic potential. However, current pharmacologic agents
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