C4786
Cefoxitin sodium salt
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About This Item
Empirical Formula (Hill Notation):
C16H16N3NaO7S2
CAS Number:
Molecular Weight:
449.43
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
251-574-6
MDL number:
form
powder or granules
Quality Level
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
storage temp.
2-8°C
SMILES string
[Na+].CO[C@]2(NC(=O)Cc1cccs1)C3SCC(COC(N)=O)=C(N3C2=O)C([O-])=O
InChI
1S/C16H17N3O7S2.Na/c1-25-16(18-10(20)5-9-3-2-4-27-9)13(23)19-11(12(21)22)8(6-26-15(17)24)7-28-14(16)19;/h2-4,14H,5-7H2,1H3,(H2,17,24)(H,18,20)(H,21,22);/q;+1/p-1/t14-,16+;/m1./s1
InChI key
GNWUOVJNSFPWDD-XMZRARIVSA-M
General description
Cefoxitin is a β-lactam that belongs to the group of cephamycin antibiotics and is considered a 2nd generation cephalosporin. It shows resistance to β-lactamases and is used to treat a broad spectrum of bacterial infections caused by gram-positive and gram-negative bacteria, such as bronchitis, pharyngitis, meningitis, and urinary tract infection among others. It is used for intravenous and intramuscular injections. It is found to be active against Bacteroides and is therapeutically used for the treatment of mixed aerobic-anaerobic infections.
Application
The analytical standard can be used to:
- Determine cefoxitin sodium using four stability-indicating spectrophotometric methods in the presence of its alkaline degradation products in its pure form and pharmaceutical dosage forms
- Separate and measure cefoxitin sodium in commercial drug products by high-performance liquid chromatography (HPLC)
Other Notes
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1B
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Murillo.A.J, et al.
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