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Merck

88315

Thesit®

Synonym(s):

Polyethylene glycol dodecyl ether, Polyethylene glycol 400 dodecyl ether, Hydroxypolyethoxydodecane, Lauromacrogol, Macrogol lauryl ether, Polidocanol

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About This Item

Linear Formula:
HO(CH2CH2O)n(CH2)11CH3
CAS Number:
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
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description

non-ionic

Quality Segment

form

solid

mol wt

average mol wt 583

impurities

≤1 ppm peroxides (as H2O2)

CMC

0.1 mM (20-25°C)

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C58H118O24/c1-2-3-4-5-6-7-8-9-10-11-13-60-15-17-62-19-21-64-23-25-66-27-29-68-31-33-70-35-37-72-39-41-74-43-45-76-47-49-78-51-53-80-55-57-82-58-56-81-54-52-79-50-48-77-46-44-75-42-40-73-38-36-71-34-32-69-30-28-67-26-24-65-22-20-63-18-16-61-14-12-59/h59H,2-58H2,1H3

InChI key

IEQAICDLOKRSRL-UHFFFAOYSA-N

Application

Suggested substitute for Lubrol in the preparation of G protein from bovine brain.
Thesit has been used in the reaction buffer to reduce the background sedimentation.

Biochem/physiol Actions

Thesit/Polidocanol possesses in vitro and in vivo anti-angiogenic effects. This sclerosant is mainly used for sclerotherapy.

Legal Information

Thesit is a registered trademark of Desitin Arzneimittel GmbH


signalword

Warning

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

pictograms

Exclamation mark

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2



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