D2158
Histodenz™
nonionic density gradient medium
Synonym(s):
5-(N-2,3-Dihydroxypropylacetamido)-2,4,6-triiodo-N,N′-bis(2,3-dihydroxypropyl)isophthalamide
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About This Item
Empirical Formula (Hill Notation):
C19H26I3N3O9
CAS Number:
Molecular Weight:
821.14
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
EC Number:
266-164-2
Beilstein/REAXYS Number:
2406632
MDL number:
Quality Segment
form
powder
application(s)
hematology
histology
storage temp.
room temp
SMILES string
CC(=O)N(CC(O)CO)c1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I
InChI
1S/C19H26I3N3O9/c1-8(29)25(4-11(32)7-28)17-15(21)12(18(33)23-2-9(30)5-26)14(20)13(16(17)22)19(34)24-3-10(31)6-27/h9-11,26-28,30-32H,2-7H2,1H3,(H,23,33)(H,24,34)
InChI key
NTHXOOBQLCIOLC-UHFFFAOYSA-N
General description
HistoDenz™, also known as iohexol, is a non-ionic X-ray contrast compound developed specifically as an iodinated density gradient medium.
Application
HistoDenz™ is suitable for separating everything from macromolecules to viable cells by either rate-zonal or isopycnic centrifugation.
- It has been used in the isolation and culturing of hepatic stellate cells.
- It has also been employed in the extraction of microbial cells from environmental samples.
- It has been used in LacZ (β-galactosidase) staining.
- It has also been used for the enrichment of gonocytes.
Features and Benefits
HistoDenz™ offers several favorable properties as a gradient medium.
- It has very low toxicity, low osmolality, high density, and low viscosity (compared to sucrose).
- It is water-soluble, non-ionic, and chemically near-inert.
Legal Information
Histodenz is a trademark of Sigma-Aldrich Co. LLC
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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