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G7879

D-Glucose 6-phosphate sodium salt

≥98% (HPLC)

Synonym(s):

D(+)-Glucopyranose 6-phosphate sodium salt, G-6-P Na, Robison ester

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About This Item

Empirical Formula (Hill Notation):
C6H12NaO9P
CAS Number:
54010-71-8
Molecular Weight:
282.12
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
24895324
EC Number:
258-921-0
Beilstein/REAXYS Number:
5787568
MDL number:
MFCD00006611
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biological source

synthetic (organic)

Quality Level

300

assay

≥98% (HPLC)

form

crystalline

technique(s)

HPLC: suitable

color

white

useful pH range

4.0-5.0

mp

204 °C (dec.) (lit.)

solubility

water: 50 mg/mL, clear, colorless to very faintly yellow

cation traces

Na: 6.1-10.2% (anhydrous)

application(s)

advanced drug delivery

storage temp.

room temp

SMILES string

[Na+].O[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C6H13O9P.Na/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;/h2-10H,1H2,(H2,11,12,13);/q;+1/p-1/t2-,3-,4+,5-,6-;/m1./s1

InChI key

ZALKNDISPIVVKC-WYRLRVFGSA-M

Application

D-glucose-6-phosphate sodium can be used as an energy source for Mycobacterium tuberculosis.

Biochem/physiol Actions

In cells, D-glucose 6-phosphate (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the beginning of both glycolysis and the pentose phosphate pathways. It also can be stored as glycogen when blood glucose levels are high.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Disclaimer

Non-hygroscopic, and very stable to atmospheric moisture at room temperature, unlike the disodium salt.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Protocols

Enzymatic Activity of Glucose-6-Phosphatase [EC 3.1.3.9]

To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.

Enzymatic Assay of Glucose-6-Phosphate Dehydrogenase (EC 1.1.1.49)

To measure glucose-6-phosphate dehydrogenase activity, beta-nicotinamide adenine dinucleotide phosphate is used in a spectrophotometric rate determination assay at 340 nm.

Articles

Aerobic Glycolysis and the Warburg Effect

Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.