P0359
Palmitoylethanolamide
≥98% (HPLC), powder, cannabinoid receptor agonist
Synonym(s):
N-(2-Hydroxyethyl)hexadecanamide, PEA, Palmidrol
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About This Item
Empirical Formula (Hill Notation):
C18H37NO2
CAS Number:
Molecular Weight:
299.49
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
208-867-9
MDL number:
Form:
powder
Quality level:
Product Name
Palmitoylethanolamide,
form
powder
Quality Level
storage temp.
−20°C
SMILES string
CCCCCCCCCCCCCCCC(=O)NCCO
InChI
1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
InChI key
HXYVTAGFYLMHSO-UHFFFAOYSA-N
Gene Information
human ... CNR1(1268), CNR2(1269)
rat ... Faah(29347)
Application
Palmitoylethanolamide has been used as a reference standard in mass spectrometry (MS/MS).
Biochem/physiol Actions
Palmitoylethanolamide (PEA) is a natural fatty acid amide of ethanolamine and palmitic acid. It is found in soybeans, egg yolk, and many other food sources. PEA is an endogenous cannabinoid receptor agonist. It is a peroxisome proliferator-activated receptor α (PPAR-α) ligand. PEA possesses anti-inflammatory, anti-allergic, neuroprotective, and analgesic activities. It belongs to the class of lipid mediators and the N-acylethanolamine family. PEA blocks the release of pro-inflammatory mediators from activated mast cells and prevents the recruitment of activated mast cells at the site of nerve injury.
Other Notes
Structural analog of anandamide.
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signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Storage Class
11 - Combustible Solids
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