495455
Oligomycin
≥90% (mixture of A, B, and C isomers, HPLC), powder, Antibiotic, Calbiochem
동의어(들):
Oligomycin
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크기 선택
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C45H74O11
CAS 번호:
Molecular Weight:
791.06
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥90% (mixture of A, B, and C isomers, HPLC)
Form:
powder
Storage condition:
OK to freeze
제품 이름
Oligomycin, A mixture of A, B, and C isomers.
Quality Segment
assay
≥90% (mixture of A, B, and C isomers, HPLC)
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
shipped in
ambient
storage temp.
−20°C
InChI
1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15-,21-18+
InChI key
MNULEGDCPYONBU-ZUSSGZTJSA-N
General description
A mixture of A, B, and C isomers. A macrolide antibiotic that inhibits membrane-bound mitochondrial ATP synthase, preventing phosphoryl group transfer. Induces apoptosis in cultured human lymphoblastoid and other mammalian cells.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Membrane-bound mitochondrial ATPase (F1)
Membrane-bound mitochondrial ATPase (F1)
Product does not compete with ATP.
Reversible: no
Preparation Note
Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 2 months at -20°C.
Other Notes
Wolvetang, E.J., et al. 1994. FEBS Lett.339, 40.
Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther.264, 515.
Brustovetsky, N.N., et al. 1993. FEBS Lett.315, 233.
Nagamune, H., et al. 1993. Biochim. Biophys. Acta1141, 231.
Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther.264, 515.
Brustovetsky, N.N., et al. 1993. FEBS Lett.315, 233.
Nagamune, H., et al. 1993. Biochim. Biophys. Acta1141, 231.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable