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Merck

235989

Brij® L4

average Mn ~362

동의어(들):

Polyethylene glycol dodecyl ether, Polyoxyethylene (4) lauryl ether

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
(C20H42O5)n
CAS 번호:
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12161900
MDL number:
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도움 문의

description

non-ionic

Quality Level

form

solid or liquid

mol wt

average Mn ~362

impurities

≤1% Water

refractive index

n20/D 1.451 (lit.)

mp

48 °C

solubility

water: insoluble

density

0.95 g/mL at 25 °C (lit.)

HLB

9

SMILES string

CCCCCCCCCCCCOCCOCCOCCOCCO

InChI

1S/C20H42O5/c1-2-3-4-5-6-7-8-9-10-11-13-22-15-17-24-19-20-25-18-16-23-14-12-21/h21H,2-20H2,1H3

InChI key

WPMWEFXCIYCJSA-UHFFFAOYSA-N

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General description

Brij® L4 is a non-ionic surfactant. It comprises an alkyl (C12) tail attached to an oxyethylene headgroup.

Application

Brij® L4 has been used:
  • as a surfactant for the synthesis of copper(I) oxide (Cu2O) spherical nanoparticles using a microemulsion technique
  • as a non-ionic surfactant for preparing reverse micelles to synthesize Pt3Co alloy nanoparticles
  • as a surfactant to enhance the efficiency of interfacial coupling of hydrophobic materials and to make hydrogel

Biochem/physiol Actions

Brij® L4 exhibits amphiphilic properties. Brij L4 contains hydrophobic and hydrophilic regions that can form micelles and disperse hydrophobic drugs into the core of micelles. This in turn enhances drug solubility. Brij L4 also elicits a strong inhibitory effect against breast cancer resistance protein (BCRP) mediated drug efflux. It inhibits Taq adsorption better when compared to other commonly used surfactants. Brij L4 supports droplet polymerase chain reaction (PCR) in picoliter reaction volumes at standard Taq concentrations.

Legal Information

Brij is a registered trademark of Croda International PLC

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2

저장 등급

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Darío Morais et al.
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Hereditary Haemorrhagic Telangiectasia or Rendu-Osler-Weber syndrome is a rare autosomal dominant vascular disease characterized by mucocutaneous and gastrointestinal telangiectases and localized arteriovenous malformations in lung, brain and liver. Epistaxis, due to rupture of telangiectases of the nasal mucosa, is the
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B McAree et al.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 43(6), 721-725 (2012-04-18)
To compare the half-life of STD and polidocanol air-based foams and the damage they inflict upon human great saphenous vein in an in-vitro model. The time for the volume of 3% STD and polidocanol foams to reduce by 10% (T(90))
L Lund et al.
The Journal of urology, 191(5), 1347-1350 (2013-11-23)
We evaluate whether aspiration and sclerosing of hydrocele testis is an effective treatment. Men with symptomatic hydrocele testis were included in this prospective, double-blind, randomized study with polidocanol and placebo. Patients were randomized to active treatment or placebo at the
Alessandro Frullini et al.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 38(5), 741-747 (2012-05-01)
Foam sclerotherapy has been proven to be a safe and effective treatment for superficial venous insufficiency, but transient visual and neurologic disturbances continue to be reported. These side effects have been theorized to be related to the presence of air

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