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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
2-(HO)C6H4CO2H
CAS 번호:
Molecular Weight:
138.12
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-712-3
MDL number:
Beilstein/REAXYS Number:
774890
Assay:
≥99.0%
제품 이름
Salicylic acid, ACS reagent, ≥99.0%
InChI key
YGSDEFSMJLZEOE-UHFFFAOYSA-N
InChI
1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
SMILES string
OC(=O)c1ccccc1O
grade
ACS reagent
vapor density
4.8 (vs air)
vapor pressure
1 mmHg ( 114 °C)
assay
≥99.0%
impurities
H2SO4, passes test (darkened)
ign. residue
≤0.01%
bp
211 °C (lit.)
Quality Level
Gene Information
human ... ALB(213), PTPN1(5770)
anion traces
chloride (Cl-): ≤0.001%, sulfate (SO42-): ≤0.003%
cation traces
Fe: ≤2 ppm, heavy metals (as Pb): ≤5 ppm
functional group
carboxylic acid
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General description
Salicylic acid is mainly used as the precursor to synthesize aspirin, a commonly used analgesic and antipyretic. Due to its keratolytic action, it is also used in topical ointments.
Application
Salicylic acid has been used:
- as one of the chemical compound in exposure-based validation of in vitro gastrulation model employed in developmental toxicity screening assays
- as a reference standard in salicylate quantification by reverse-phase high-performance liquid chromatography (RP-HPLC)
Biochem/physiol Actions
Salicylic acid (SA) delivers local and systemic acquired resistance (LAR and SAR) against various diseases in plants. It acts as a secondary metabolite and regulate various physiological processes such as respiration, stomatal closure and senescence-associated gene expression. In addition, SA also controls abiotic stress, basal thermotolerance, nodulation in legumes and fruit yield. It plays a vital role in modulation of flowering and thermogenesis (heat production) in plants. SA together with reactive oxygen species (ROS) and nitric oxide (NO) triggers cell death in plants.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2
저장 등급
11 - Combustible Solids
wgk
WGK 1
flash_point_f
314.6 °F - closed cup
flash_point_c
157 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
A central role of salicylic acid in plant disease resistance
Delaney TP, et al.
Science, 266(5188), 1247-1250 (1994)
Efficacy of salicylic acid to reduce Penicillium expansum inoculum and preserve apple fruits
da Rocha Neto AC, et al.
International Journal of Food Microbiology, 221, 54-60 (2016)
Influence of cyclooxygenase-1 genotype on ex vivo aspirin response in patients at risk for stroke
Momary KM, et al.
Cerebrovascular Diseases (Basel, Switzerland), 27(6), 585-593 (2009)
Xanthone
AF Holleman
Organic Syntheses, 1, 552-552 (1941)
Isochorismate synthase is required to synthesize salicylic acid for plant defence
Wildermuth MC, et al.
Nature, 414(6863), 562-562 (2001)
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