47673
Formaldehyde solution
tested according to Ph. Eur.
동의어(들):
Formalin
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
HCHO
CAS 번호:
Molecular Weight:
30.03
UNSPSC Code:
12352114
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1209228
Form:
liquid
InChI
1S/CH2O/c1-2/h1H2
SMILES string
[H]C([H])=O
InChI key
WSFSSNUMVMOOMR-UHFFFAOYSA-N
Quality Level
agency
tested according to Ph. Eur.
vapor density
1.03 (vs air)
vapor pressure
52 mmHg ( 37 °C)
form
liquid
autoignition temp.
572 °F
contains
9.0-15.0 % (v/v) methanol as stabilizer
concentration
25-50%
solubility
water: soluble
density
1.09 g/mL at 25 °C (lit.)
suitability
suitable for manufacturing use (Laboratory chemicals)
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Application
Formaldehyde solution has been used to fix labeled cells during flow cytometry.
Biochem/physiol Actions
Formaldehyde is the simplest aldehyde that denatures the bihelical regions of RNA and converts the polynucleotides into random coils. It is a genotoxic substance that significantly induces DNA-protein crosslinks (DPC), sister-chromatid exchanges, micronuclei formation and leads to cytotoxicity. It also induces tumors in the nasal epithelium of rats and supposed to be a human carcinogen.
Disclaimer
may become turbid on storage
signalword
Danger
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3
target_organs
Eyes,Central nervous system, Respiratory system
저장 등급
3 - Flammable liquids
wgk
WGK 3
flash_point_f
133.0 °F - closed cup
flash_point_c
56.11 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Dependence of the sedimentation coefficient on molecular weight of RNA after reaction with formaldehyde.
H Boedtker
Journal of molecular biology, 35(1), 61-70 (1968-07-14)
O Merk et al.
Environmental and molecular mutagenesis, 32(3), 260-268 (1998-11-14)
Formaldehyde (FA) is a genotoxic substance, induces tumors in the nasal epithelium of rats, and is suspected to be a human carcinogen. As a primary DNA lesion, FA induces DNA-protein crosslinks (DPC) and the formation of DPC has been used
J L Wilson et al.
Journal of immunology (Baltimore, Md. : 1950), 163(12), 6365-6370 (1999-12-10)
NK cells have the capacity to spontaneously kill tumor cell lines, in particular cell lines of hemopoietic origin. In contrast, they do not generally kill nontransformed autologous cells. However, here we demonstrate that short-term activated polyclonal human NK cells, as
Cindy S Ma et al.
The Journal of experimental medicine, 205(7), 1551-1557 (2008-07-02)
Hyper-immunoglobulin E syndrome (HIES) is a primary immune deficiency characterized by abnormal and devastating susceptibility to a narrow spectrum of infections, most commonly Staphylococcus aureus and Candida albicans. Recent investigations have identified mutations in STAT3 in the majority of HIES
G R Moore et al.
Neurology, 55(10), 1506-1510 (2000-11-30)
To determine the pathologic basis of areas not exhibiting signal of the short-T2 component of the T2 relaxation distribution in MS, as studied in formalin-fixed brain. A myelin-specific MRI signal would be of great importance in assessing demyelination in patients
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